Table 1. First latency data of EQ,... | Rockefeller University Press

Table 1.

First latency data of EQ, S209F, S27D, S27D/S92D, and Q1+E1 before and after 200 µM 8-CPT-cAMP/0.2 µM OA

Construct	Control					8-CPT-cAMP/OA					P-value	Cells
	First latency			Active sweeps	Total sweeps	First latency			Active sweeps	Total sweeps		Cells
	Mean ± SE (s)	95% CI of the mean (lower to upper)	Median (s)	n	n	Mean ± SE (s)	95% CI of the mean (lower to upper)	Median (s)	n	n		n
EQ	1.61 ± 0.13	1.35–1.87	1.57	43	367	1.06 ± 0.11	0.84–1.27	0.85	69	345	0.0005	3
S209F+E1	0.16 ± 0.05	0.07–0.25	0.07	67	128	0.18 ± 0.06	0.06–0.30	0.04	85	220	0.0208	2
S27D+E1	1.81 ± 0.13	1.55–2.08	1.60	57	302	1.44 ± 0.11	1.22–1.66	1.10	67	335	0.0320	3
Q1+E1	1.32 ± 0.13	1.06–1.57	0.90	68	278	0.79 ± 0.08	0.63–0.95	0.50	104	309	0.0002	3
S27D/S92D+E1	1.62 ± 0.08	1.46–1.78	1.40	189	467	1.43 ± 0.13	1.18–1.69	1.26	60	119	0.332	3–5

Construct	Control					8-CPT-cAMP/OA					P-value	Cells
	First latency			Active sweeps	Total sweeps	First latency			Active sweeps	Total sweeps		Cells
	Mean ± SE (s)	95% CI of the mean (lower to upper)	Median (s)	n	n	Mean ± SE (s)	95% CI of the mean (lower to upper)	Median (s)	n	n		n
EQ	1.61 ± 0.13	1.35–1.87	1.57	43	367	1.06 ± 0.11	0.84–1.27	0.85	69	345	0.0005	3
S209F+E1	0.16 ± 0.05	0.07–0.25	0.07	67	128	0.18 ± 0.06	0.06–0.30	0.04	85	220	0.0208	2
S27D+E1	1.81 ± 0.13	1.55–2.08	1.60	57	302	1.44 ± 0.11	1.22–1.66	1.10	67	335	0.0320	3
Q1+E1	1.32 ± 0.13	1.06–1.57	0.90	68	278	0.79 ± 0.08	0.63–0.95	0.50	104	309	0.0002	3
S27D/S92D+E1	1.62 ± 0.08	1.46–1.78	1.40	189	467	1.43 ± 0.13	1.18–1.69	1.26	60	119	0.332	3–5

Latencies were obtained from 4-s sweeps at 60 mV, active sweeps only. P-values indicate difference between control and cAMP (Mann–Whitney test).