Table 2. The summary of experimentally... | Rockefeller University Press

Table 2.

The summary of experimentally determined parameters for the two PaMscS channels in comparison to EC MscS

Channel	ΔE	ΔA	P_0.5MscS/P_0.5MscL	Conductance	Selectivity P_CI/P_K	Inactivation	Recovery time
	kT	nm²		nS		%	s
EC MscS	∼20–28 (Akitake et al., 2005)	∼12–14 (Akitake et al., 2005; Boer et al., 2011)	0.58 ± 0.02 (n = 12)	∼1–1.1 (Sukharev, 2002)	∼1.5 (Sukharev, 2002)	36 ± 5 (n = 15)	1.5–3 (Akitake et al., 2005)
PaMscS-1	17.1 ± 0.5 (n = 16)	11.0 ± 0.5 (n = 16)	0.47 ± 0.01 (n = 4)	0.96 ± 0.02 (n = 3)	∼1.5 (n = 3)	40 ± 8 (n = 10)	30 ± 6 (n = 4)
PaMscS-2	15 ± 2 (n = 3)	10 ± 1 (n = 3)	0.51 ± 0.01 (n = 4)	0.55 ± 0.02 (n = 3)	∼4.4 (n = 3)	64 ± 3 (n = 7)	200 ± 70 (n = 3)

Channel	ΔE	ΔA	P_0.5MscS/P_0.5MscL	Conductance	Selectivity P_CI/P_K	Inactivation	Recovery time
	kT	nm²		nS		%	s
EC MscS	∼20–28 (Akitake et al., 2005)	∼12–14 (Akitake et al., 2005; Boer et al., 2011)	0.58 ± 0.02 (n = 12)	∼1–1.1 (Sukharev, 2002)	∼1.5 (Sukharev, 2002)	36 ± 5 (n = 15)	1.5–3 (Akitake et al., 2005)
PaMscS-1	17.1 ± 0.5 (n = 16)	11.0 ± 0.5 (n = 16)	0.47 ± 0.01 (n = 4)	0.96 ± 0.02 (n = 3)	∼1.5 (n = 3)	40 ± 8 (n = 10)	30 ± 6 (n = 4)
PaMscS-2	15 ± 2 (n = 3)	10 ± 1 (n = 3)	0.51 ± 0.01 (n = 4)	0.55 ± 0.02 (n = 3)	∼4.4 (n = 3)	64 ± 3 (n = 7)	200 ± 70 (n = 3)

The degree of inactivation was measured at saturating pressure after a 10-s conditioning pressure step of amplitude around p_0.5.