Table 1.
Cryo-EM domain nomenclature of RyR1
Domain nameAlternative namesColoraSequenceb
N-terminal domain  Yellow 1–627 
SPRY1  Light orange 628–849 
RY1 and 2 P1 Light magenta 850–1,054 
SPRY2 and 3  Light orange 1,055–1,656 
Jsol Handle Green 1,657–2,144 
Bsol HD1&2 Cyan 2,145–3,613 
 Includes RY3 and 4 P2 Orange 2,735–2,938 
Csol Central domain Tomato 3,667–4,174 
 Includes EF hand motifs   4,060–4,134 
  TaF   4,175–4,253 
Transmembrane domain  Blue 4,541–4,956 
C-terminal domain  Brown 4,957–5,037 
a

Domain color in Fig. 1.

b

des Georges et al. (2016).

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