| Construct . | at [Ca2+] . | i . | γ . | PO max . |
|---|---|---|---|---|
| pA | pS | |||
| WT | 2 µM | 0.21 ± 0.013 | 2.63 ± 0.16 | 0.71 ± 0.022 |
| 1 mM | 0.22 ± 0.0091 | 2.75 ± 0.11 | 0.87 ± 0.025 | |
| E702Q | 1 mM | 0.19 ± 0.0094 | 2.38 ± 0.12 | 0.81 ± 0.018 |
| K588E | 2 µM | 0.084 ± 0.0057 | 1.05 ± 0.071 | 0.48 ± 0.055 |
| K588E/E702Q | 1 mM | 0.16 ± 0.014 | 2.00 ± 0.18 | 0.73 ± 0.025 |
| WT_WT | 2 µM | 0.15 ± 0.0046 | 1.88 ± 0.058 | 0.62 ± 0.039 |
| WT_E654Q | 2 µM | 0.17 ± 0.018 | 2.13 ± 0.23 | 0.66 ± 0.015 |
| 1 mM | 0.196 ± 0.019 | 2.45 ± 0.24 | 0.81 ± 0.024 | |
| WT_E702Q | 2 µM | 0.14 ± 0.0084 | 1.75 ± 0.11 | 0.50 ± 0.037 |
| Construct . | at [Ca2+] . | i . | γ . | PO max . |
|---|---|---|---|---|
| pA | pS | |||
| WT | 2 µM | 0.21 ± 0.013 | 2.63 ± 0.16 | 0.71 ± 0.022 |
| 1 mM | 0.22 ± 0.0091 | 2.75 ± 0.11 | 0.87 ± 0.025 | |
| E702Q | 1 mM | 0.19 ± 0.0094 | 2.38 ± 0.12 | 0.81 ± 0.018 |
| K588E | 2 µM | 0.084 ± 0.0057 | 1.05 ± 0.071 | 0.48 ± 0.055 |
| K588E/E702Q | 1 mM | 0.16 ± 0.014 | 2.00 ± 0.18 | 0.73 ± 0.025 |
| WT_WT | 2 µM | 0.15 ± 0.0046 | 1.88 ± 0.058 | 0.62 ± 0.039 |
| WT_E654Q | 2 µM | 0.17 ± 0.018 | 2.13 ± 0.23 | 0.66 ± 0.015 |
| 1 mM | 0.196 ± 0.019 | 2.45 ± 0.24 | 0.81 ± 0.024 | |
| WT_E702Q | 2 µM | 0.14 ± 0.0084 | 1.75 ± 0.11 | 0.50 ± 0.037 |
Presented as mean ± SEM calculated from fitted parameters from individual patches.