Table 1.

Time constants and areas of the components of open- and shut-time distributions at different propylamine concentrations

Propylamine (nτ1 (area [%]) τ2 (area [%]) τ3 (area [%]) Mean open time 
mM ms ms ms ms 
Open times 
0.5 (3) 0.043 ± 0.008 (26 ± 2) 1.5 ± 0.4 (12 ± 0.5) 34 ± 6 (62 ± 3) 25 ± 5 
1 (3) 0.07 ± 0.02 (20 ± 5) 5 ± 4 (13 ± 2) 39 ± 9 (68 ± 3) 30 ± 7 
5 (3) 0.05 ± 0.02 (16 ± 2) 2 ± 1 (9 ± 1) 39 ± 5 (75 ± 3) 33 ± 5 
10 (3) 0.04 ± 0.02 (20 ± 2) 2 ± 2 (12 ± 1) 33 ± 2 (68 ± 1) 27 ± 2 
50 (3) 0.08 ± 0.03 (14 ± 5) 0.9 ± 0.3 (5 ± 3) 15 ± 2 (80 ± 9) 13 ± 2 
Propylamine (nτ1 (area [%]) τ2 (area [%]) τ3 (area [%]) τ4 (area [%]) 
mM ms ms ms ms 
Shut times 
0.5 (3) 0.010 ± 0.004 (92 ± 6) 0.11 ± 0.03 (6 ± 5) 1.1 ± 0.3 (5 ± 1) 4,000 ± 2,000 (1 ± 1) 
1 (3) 0.011 ± 0.003 (89 ± 9) 0.14 ± 0.03 (7 ± 6) 1.3 ± 0.3 (2 ± 2) 1,300 ± 300 (2 ± 2) 
5 (3) 0.014 ± 0.004 (80 ± 12) 0.14 ± 0.02 (18 ± 10) 2.2 ± 0.2 (2 ± 1) 1,100 ± 400 (0.8 ± 0.4) 
10 (3) 0.012 ± 0.002 (80 ± 8) 0.14 ± 0.02 (18 ± 7) 1.3 ± 0.4 (1.8 ± 0.4) 56 ± 4 (0.5 ± 0.3) 
50 (3) 0.06 ± 0.04 (91 ± 2) 0.15 ± 0.02 (8 ± 2) 3 ± 2 (1.1 ± 0.5)  
Propylamine (nτ1 (area [%]) τ2 (area [%]) τ3 (area [%]) Mean open time 
mM ms ms ms ms 
Open times 
0.5 (3) 0.043 ± 0.008 (26 ± 2) 1.5 ± 0.4 (12 ± 0.5) 34 ± 6 (62 ± 3) 25 ± 5 
1 (3) 0.07 ± 0.02 (20 ± 5) 5 ± 4 (13 ± 2) 39 ± 9 (68 ± 3) 30 ± 7 
5 (3) 0.05 ± 0.02 (16 ± 2) 2 ± 1 (9 ± 1) 39 ± 5 (75 ± 3) 33 ± 5 
10 (3) 0.04 ± 0.02 (20 ± 2) 2 ± 2 (12 ± 1) 33 ± 2 (68 ± 1) 27 ± 2 
50 (3) 0.08 ± 0.03 (14 ± 5) 0.9 ± 0.3 (5 ± 3) 15 ± 2 (80 ± 9) 13 ± 2 
Propylamine (nτ1 (area [%]) τ2 (area [%]) τ3 (area [%]) τ4 (area [%]) 
mM ms ms ms ms 
Shut times 
0.5 (3) 0.010 ± 0.004 (92 ± 6) 0.11 ± 0.03 (6 ± 5) 1.1 ± 0.3 (5 ± 1) 4,000 ± 2,000 (1 ± 1) 
1 (3) 0.011 ± 0.003 (89 ± 9) 0.14 ± 0.03 (7 ± 6) 1.3 ± 0.3 (2 ± 2) 1,300 ± 300 (2 ± 2) 
5 (3) 0.014 ± 0.004 (80 ± 12) 0.14 ± 0.02 (18 ± 10) 2.2 ± 0.2 (2 ± 1) 1,100 ± 400 (0.8 ± 0.4) 
10 (3) 0.012 ± 0.002 (80 ± 8) 0.14 ± 0.02 (18 ± 7) 1.3 ± 0.4 (1.8 ± 0.4) 56 ± 4 (0.5 ± 0.3) 
50 (3) 0.06 ± 0.04 (91 ± 2) 0.15 ± 0.02 (8 ± 2) 3 ± 2 (1.1 ± 0.5)  

Distributions were fitted with mixtures of exponential probability density functions. n, the number of patches for each concentration (indicated in parentheses in the first column). The time constant of each component and its relative area (in parentheses) are given as mean ± SD of the mean.

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