Table 3.

IC50 values for glibenclamide concentration-inhibition relationships of the indicated KATP channels

Channel Control +100 µM MgADP 
Kir6.2/SUR1 4.2 ± 1.1 nM (n = 6) 3.8 ± 0.7 nM (n = 6) 
Kir.2/SUR2A 15.8 ± 3.0 nM (n = 6) 29.2 ± 7.1 nM (n = 5) 
Channel Control +100 µM MgADP 
Kir6.2/SUR1 4.2 ± 1.1 nM (n = 6) 3.8 ± 0.7 nM (n = 6) 
Kir.2/SUR2A 15.8 ± 3.0 nM (n = 6) 29.2 ± 7.1 nM (n = 5) 

All values are the mean of the fits to the individual dose–response curves.

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