Effects of external [Ca2+] on single-channel kinetics
| [Ca2+] | Po | Po (1 − Pclosed) | MCT | MOT | Events | ||
| OP | OS | OP | OS | ||||
| mM | ms | ms | ms | ||||
| 0 (n = 7) | 0.38 ± 0.08 | - | 0.38 ± 0.08 | 12 ± 4 | 5.0 ± 0.6 | - | 1.6 × 106 |
| 1.8 (n = 5) | 0.26 ± 0.04 | 0.006 ± 0.001 | 0.27 ± 0.03 | 16 ± 4 | 4.9 ± 0.6 | 2.6 ± 0.4 | 1.9 × 106 |
| 5 (n = 6) | 0.13 ± 0.06a | 0.007 ± 0.003 | 0.14 ± 0.06a | 70 ± 30a | 4.0 ± 0.7 | 2.8 ± 0.7 | 3.4 × 105 |
| 75 (n = 7) | 0.18 ± 0.06a | 0.02 ± 0.01a | 0.20 ± 0.07 | 200 ± 100a | 6.4 ± 0.7 | 3.5 ± 0.3a | 2.3 × 105 |
| [Ca2+] | Po | Po (1 − Pclosed) | MCT | MOT | Events | ||
| OP | OS | OP | OS | ||||
| mM | ms | ms | ms | ||||
| 0 (n = 7) | 0.38 ± 0.08 | - | 0.38 ± 0.08 | 12 ± 4 | 5.0 ± 0.6 | - | 1.6 × 106 |
| 1.8 (n = 5) | 0.26 ± 0.04 | 0.006 ± 0.001 | 0.27 ± 0.03 | 16 ± 4 | 4.9 ± 0.6 | 2.6 ± 0.4 | 1.9 × 106 |
| 5 (n = 6) | 0.13 ± 0.06a | 0.007 ± 0.003 | 0.14 ± 0.06a | 70 ± 30a | 4.0 ± 0.7 | 2.8 ± 0.7 | 3.4 × 105 |
| 75 (n = 7) | 0.18 ± 0.06a | 0.02 ± 0.01a | 0.20 ± 0.07 | 200 ± 100a | 6.4 ± 0.7 | 3.5 ± 0.3a | 2.3 × 105 |
P < 0.05 relative to 0 mM Ca2+ for OP and relative to 1.8 mM Ca2+ for OS (unpaired t test).