Table 1. Reversal potentials of WT-CFTR... | Rockefeller University Press

Table 1.

Reversal potentials of WT-CFTR and mutants in ND96 bath solution

CFTR	n	V_rev
		mV
WT	14	−27.75 ± 0.78
R334A	6	−12.15 ± 1.64^a
R117A	6	−22.51 ± 0.85^a
E116R	5	−21.45 ± 1.14^a
K114D	5	−24.68 ± 3.22
D110R	5	−27.64 ± 3.29
R104E	5	−21.15 ± 1.08^a
R899C	4	−25.30 ± 3.94
D891C	6	−25.81 ± 2.44
K892E	5	−23.70 ± 3.62
E1124R	5	−18.32 ± 0.43^a
E1126R	5	−20.67 ± 3.16^b
R117E/E1126R	6	−23.06 ± 1.37^b
R104E/E116R	6	−27.17 ± 1.08

CFTR	n	V_rev
		mV
WT	14	−27.75 ± 0.78
R334A	6	−12.15 ± 1.64^a
R117A	6	−22.51 ± 0.85^a
E116R	5	−21.45 ± 1.14^a
K114D	5	−24.68 ± 3.22
D110R	5	−27.64 ± 3.29
R104E	5	−21.15 ± 1.08^a
R899C	4	−25.30 ± 3.94
D891C	6	−25.81 ± 2.44
K892E	5	−23.70 ± 3.62
E1124R	5	−18.32 ± 0.43^a
E1126R	5	−20.67 ± 3.16^b
R117E/E1126R	6	−23.06 ± 1.37^b
R104E/E116R	6	−27.17 ± 1.08

Values are mean ± SEM. n, number of oocytes. V_rev, reversal potential for Cl⁻.

P < 0.001 compared with WT-CFTR by t test.

P < 0.01 compared with WT by t test.