The Hill fit parameters for cytoplasmic Ca2+ activation of RyR2 in the presence of 1 mM Mg2+ shown in Fig. 3 A
| Species | Luminal pCa | Pmax | Pmin | Ka | Ha | n |
| µM | ||||||
| Activation by cytoplasmic Ca2+ | ||||||
| Human | 4 | 0.55 ± 0.10 | 0a | 25 ± 8 | 2.6 ± 0.6 | 4–8 |
| Sheep | 4 | 0.70 ± 0.10 | 0a | 34 ± 5 | 2.2 ± 0.2 | 5–10 |
| Rat | 4 | 0.54 ± 0.06 | 0a | 88 ± 9b | 3.5 ± 0.4 | 4–7 |
| Species | Luminal pCa | |||||
| Human | 4 | 0.55 ± 0.10 | 0 | 25 ± 8 | 2.6 ± 0.6 | 4–8 |
| Sheep | 4 | 0.70 ± 0.10 | 0 | 34 ± 5 | 2.2 ± 0.2 | 5–10 |
| Rat | 4 | 0.54 ± 0.06 | 0 | 88 ± 9 | 3.5 ± 0.4 | 4–7 |
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