Table 3. The Hill fit parameters for... | Rockefeller University Press

Table 3.

The Hill fit parameters for luminal regulation data shown in Fig. 2

Species	[Ca²⁺]_L pCa	[Ca²⁺]_C pCa	P_max	P_min (×10³)	K_a/K_i	H_a/H_i	n
					µM
Activation by luminal Ca²⁺
Human	-	7	0.14 ± 0.03	0.8 ± 0.3	35 ± 12	1.3 ± 0.2	3–17
Sheep	-	7	0.19 ± 0.05	0.9 ± 0.4	12 ± 3	2^a	3–11
Rat	-	7	0.013 ± 0.003^b	0.3 ± 0.1	10 ± 7	2^a	3–16
Inhibition by luminal Mg²⁺
Human	4	7	0.09 ± 0.02	0^a	550 ± 30	3.8 ± 1.8	5–6
Sheep	4	7	0.10 ± 0.04	0^a	650 ± 80	2.0 ± 1.0	4–11
Rat	4	7	0.023 ± 0.011^c	0^a	78 ± 14^b	1.3 ± 0.5	7

Species	[Ca²⁺]_L pCa	[Ca²⁺]_C pCa	P_max	P_min (×10³)	K_a/K_i	H_a/H_i	n
					µM
Activation by luminal Ca²⁺
Human	-	7	0.14 ± 0.03	0.8 ± 0.3	35 ± 12	1.3 ± 0.2	3–17
Sheep	-	7	0.19 ± 0.05	0.9 ± 0.4	12 ± 3	2^a	3–11
Rat	-	7	0.013 ± 0.003^b	0.3 ± 0.1	10 ± 7	2^a	3–16
Inhibition by luminal Mg²⁺
Human	4	7	0.09 ± 0.02	0^a	550 ± 30	3.8 ± 1.8	5–6
Sheep	4	7	0.10 ± 0.04	0^a	650 ± 80	2.0 ± 1.0	4–11
Rat	4	7	0.023 ± 0.011^c	0^a	78 ± 14^b	1.3 ± 0.5	7

n indicates the number of experiments. Hill parameters for luminal Ca²⁺ inhibition at luminal approximately pCa 3 were poorly determined and not shown.

Parameters that were not adjusted during fitting.

Significantly different to human (P < 0.01).

Significantly different to human (P < 0.05).

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