Summary of cell-SPOC parameters used for the discussion on the experimental findings of OM
| Parameter | Physiological meaning | +OM | ||
| Parameter change | Amplitude | Frequency | ||
| α | Crossbridge attachment rate | ↑ | ↑ | ↓ |
| η | Molecular frictional constant for crossbridge formation | ↑ | ↓ | ↓ |
| Parameter | Physiological meaning | +OM | ||
| Parameter change | Amplitude | Frequency | ||
| α | Crossbridge attachment rate | ↑ | ↑ | ↓ |
| η | Molecular frictional constant for crossbridge formation | ↑ | ↓ | ↓ |
Our mathematical model (Sato et al., 2011) predicts that OM decreases frequency via an increase in α and an increase in η, but the compound hardly changes amplitude because the effect of an increase in α is offset by that of an increase in η (see Results and discussion). Amplitude, cell-SPOC amplitude; frequency, cell-SPOC frequency. Arrows, directions of change.