Table 2. MHC isoform composition as... | Rockefeller University Press

Table 2.

MHC isoform composition as quantified by Coomassie stain of protein lysates

Muscle	IIA + IIX	IIB/N	I
	%	%	%
Soleus (3 mo)
WT	60 ± 2.2	2 ± 0.5	37 ± 2.3
KO	40 ± 3.1^a	2 ± 0.4	57 ± 2.8^a
Diaphragm (3 mo)
WT	76 ± 2.8	16 ± 3.4	6.8 ± 0.9
KO	85 ± 4.9	12 ± 5.1	1.5 ± 0.5^b
EDL (3 mo)
WT	17 ± 1.2	82 ± 1.2	0
KO	19 ± 1.2	80 ± 1.2	0
TC (3 mo)
WT	23 ± 5.1	76 ± 5.1	0
KO	28 ± 6.7	71 ± 6.7	0
Soleus (5 d)
WT	35 ± 1.6	45 ± 1.4	18 ± 0.1
KO	34 ± 1.7	49 ± 1.4	15 ± 0.2

Muscle	IIA + IIX	IIB/N	I
	%	%	%
Soleus (3 mo)
WT	60 ± 2.2	2 ± 0.5	37 ± 2.3
KO	40 ± 3.1^a	2 ± 0.4	57 ± 2.8^a
Diaphragm (3 mo)
WT	76 ± 2.8	16 ± 3.4	6.8 ± 0.9
KO	85 ± 4.9	12 ± 5.1	1.5 ± 0.5^b
EDL (3 mo)
WT	17 ± 1.2	82 ± 1.2	0
KO	19 ± 1.2	80 ± 1.2	0
TC (3 mo)
WT	23 ± 5.1	76 ± 5.1	0
KO	28 ± 6.7	71 ± 6.7	0
Soleus (5 d)
WT	35 ± 1.6	45 ± 1.4	18 ± 0.1
KO	34 ± 1.7	49 ± 1.4	15 ± 0.2

Data are represented as percentage of total MHC (n = 8 WT and 8 KO).

P < 0.001.

P < 0.01.