Table 2. Accessory subunits and selected... | Rockefeller University Press

Table 2.

Accessory subunits and selected ion channel adapter proteins

Channel	Subunit	Gene	Candidate S-acylation sites	UniProt ID	References
Voltage gated
Calcium	CaVβ2a	Cacnb2	¹MQCCGLVHRRRVRV	Q8CC27	Chien et al., 1996; Stephens et al., 2000; Heneghan et al., 2009; Mitra-Ganguli et al., 2009
Potassium	KChip2	Kcnip2	³⁴LKQRFLKLLPCCGPQALPSVSE	Q9JJ69	Takimoto et al., 2002
	KChip3	Kcnip3	³⁵PRFTRQALMRCCLIKWILSSAA	Q9QXT8	Takimoto et al., 2002
	BK β4	Kcnmb4	¹⁹³VGVLIVVLTICAKSLAVKAEA	Q9JIN6	Chen et al., 2013
Adapter proteins that interact with ion channels	PICK1	Pick1	⁴⁰⁴TGPTDKGGSWCDS-stop	Q62083	Thomas et al., 2013
	Grip1b	Grip1	¹MPGWKKNIPICLQAEEQERE	Q925T6-2	Thomas et al., 2012; Yamazaki et al., 2001
	psd-95	Dlg4	¹MDCLCIVTTKKYR	Q62108	Topinka and Bredt, 1998
	S-delphilin	Grid2ip	¹MSCLGIFIPKKH	Q0QWG9-2	Matsuda et al., 2006
	Ankyrin-G	Ank3	⁶⁰YIKNGVDVNICNQNGLNALHL	F1LNM3	He et al., 2012

Channel	Subunit	Gene	Candidate S-acylation sites	UniProt ID	References
Voltage gated
Calcium	CaVβ2a	Cacnb2	¹MQCCGLVHRRRVRV	Q8CC27	Chien et al., 1996; Stephens et al., 2000; Heneghan et al., 2009; Mitra-Ganguli et al., 2009
Potassium	KChip2	Kcnip2	³⁴LKQRFLKLLPCCGPQALPSVSE	Q9JJ69	Takimoto et al., 2002
	KChip3	Kcnip3	³⁵PRFTRQALMRCCLIKWILSSAA	Q9QXT8	Takimoto et al., 2002
	BK β4	Kcnmb4	¹⁹³VGVLIVVLTICAKSLAVKAEA	Q9JIN6	Chen et al., 2013
Adapter proteins that interact with ion channels	PICK1	Pick1	⁴⁰⁴TGPTDKGGSWCDS-stop	Q62083	Thomas et al., 2013
	Grip1b	Grip1	¹MPGWKKNIPICLQAEEQERE	Q925T6-2	Thomas et al., 2012; Yamazaki et al., 2001
	psd-95	Dlg4	¹MDCLCIVTTKKYR	Q62108	Topinka and Bredt, 1998
	S-delphilin	Grid2ip	¹MSCLGIFIPKKH	Q0QWG9-2	Matsuda et al., 2006
	Ankyrin-G	Ank3	⁶⁰YIKNGVDVNICNQNGLNALHL	F1LNM3	He et al., 2012

Common channel abbreviation and subunit as well as gene names are given. Candidate S-acylation sites: experimentally determined cysteine residues (bold) with flanking 10 amino acids. Underlines indicate predicted transmembrane domains. Amino acid numbering corresponds to the UniProt ID. References: selected original supporting citations.

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