Table 2.

AP measurements

Mouse line Rmax pre Rmax post % Increase τrec 
 pA pA  s 
WT (15) 13.9 ± 1.2 18.4 ± 1.5 31 ± 3 6.8 ± 0.7 
CaMΔ (16) 11.2 ± 0.9 17.7 ± 1.4 59 ± 4a 8.5 ± 0.8 
GCAP−/− (13) 10.8 ± 1.1 17.8 ± 1.9 68 ± 8a 4.3 ± 0.9 
Mouse line Rmax pre Rmax post % Increase τrec 
 pA pA  s 
WT (15) 13.9 ± 1.2 18.4 ± 1.5 31 ± 3 6.8 ± 0.7 
CaMΔ (16) 11.2 ± 0.9 17.7 ± 1.4 59 ± 4a 8.5 ± 0.8 
GCAP−/− (13) 10.8 ± 1.1 17.8 ± 1.9 68 ± 8a 4.3 ± 0.9 

AP elicited by a 3-min conditioning stimulus was calculated. Rmax pre represents dark-adapted mean amplitude before light exposure. Rmax post indicates the mean potentiated amplitude immediately after light exposure. The % increase indicates the mean increase in maximum current. τrec refers to the time constant of recovery of the potentiated amplitudes back to dark-adapted amplitudes. The conditioning stimulus intensity was selected to just saturate the rod in each experiment.

a

Significant difference from WT (P < 0.001).

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