Relative changes in [3H]ouabain binding and the α2 subunit of Na+,K+-ATPase in skeletal muscle
| References, muscle preparation, treatment | [3H]Ouabain binding | α2-subunit abundance |
| Thompson et al., 2001, rats treated for 14 d with dexamethasone | +22–48% (P < 0.05) | +53% (P < 0.05) |
| Juel et al, 2001, 1 h treadmill running 150-200 g rats, giant vesicles | +29% (P < 0.05) | +32% (P < 0.05) |
| Green et al., 2004, 6 d submaximal cycling | +13% (P < 0.05) | +9% (P < 0.05) |
| Sandiford et al., 2005, electrical stimulation of rat soleus | +16–21% (P < 0.05) | +38% (P < 0.05) |
| Green et al., 2007, 16 h heavy intermittent cycling | +8% (P < 0.05) | +26% (P < 0.05) |
| Green et al., 2008, 3 d submaximal cycling | +12% (P < 0.05) | +42% (P < 0.05) |
| Green et al., 2009, chronic obstructive lung disease | −6% (NS) | +12% (P < 0.05) |
| McKenna et al., 2012, young compared to aged subjects | −0.7% (NS) | −24% (P < 0.05) |
| Boon et al., 2012, spinal cord injury in human subject | −47% (P < 0.05) | −52% (P < 0.05) |
| Chibalin et al., 2012, nicotine pretreatment in 190 g rats | 0% (NS) | −25% (P < 0.05) |
| References, muscle preparation, treatment | [3H]Ouabain binding | α2-subunit abundance |
| Thompson et al., 2001, rats treated for 14 d with dexamethasone | +22–48% (P < 0.05) | +53% (P < 0.05) |
| Juel et al, 2001, 1 h treadmill running 150-200 g rats, giant vesicles | +29% (P < 0.05) | +32% (P < 0.05) |
| Green et al., 2004, 6 d submaximal cycling | +13% (P < 0.05) | +9% (P < 0.05) |
| Sandiford et al., 2005, electrical stimulation of rat soleus | +16–21% (P < 0.05) | +38% (P < 0.05) |
| Green et al., 2007, 16 h heavy intermittent cycling | +8% (P < 0.05) | +26% (P < 0.05) |
| Green et al., 2008, 3 d submaximal cycling | +12% (P < 0.05) | +42% (P < 0.05) |
| Green et al., 2009, chronic obstructive lung disease | −6% (NS) | +12% (P < 0.05) |
| McKenna et al., 2012, young compared to aged subjects | −0.7% (NS) | −24% (P < 0.05) |
| Boon et al., 2012, spinal cord injury in human subject | −47% (P < 0.05) | −52% (P < 0.05) |
| Chibalin et al., 2012, nicotine pretreatment in 190 g rats | 0% (NS) | −25% (P < 0.05) |
Data were obtained from 10 different publications listed in the references of this paper. Each of them was selected for reporting the results of measurements of the content of [3H]ouabain-binding sites as well as α2-subunit abundance in the same muscle. Experimental details are given in the cited articles. The relative changes induced by the listed factors are given in percentages. Biopsies from human subjects were taken from the vastus lateralis muscle. The rat muscles were obtained from the hind limbs.