Table 1. Estimates of dynamic... | Rockefeller University Press

Table 1.

Estimates of dynamic contractile parameters from α- and β-MHC–containing fibers reconstituted with RcTnT_1–43Δ and RcTnT_44–73Δ

Dynamic contractile parameters	RcTnT_WT	RcTnT_1–43Δ	RcTnT_44–73Δ
α-MHC
b (s⁻¹)	18.14 ± 0.62	18.38 ± 1.10	17.46 ± 0.43
k_tr (s⁻¹)	7.32 ± 0.17	7.25 ± 0.31	6.79 ± 0.29
c (s⁻¹)	21.41 ± 0.83	20.60 ± 1.53	20.14 ± 0.07
β-MHC
b (s⁻¹)	7.55 ± 0.34^a	7.84 ± 0.17^a	7.53 ± 0.22^a
k_tr (s⁻¹)	4.15 ± 0.11^a	4.38 ± 0.08^a	4.40 ± 0.11^a
c (s⁻¹)	10.72 ± 0.40^a	10.70 ± 0.35^a	11.68 ± 0.30^a

Dynamic contractile parameters	RcTnT_WT	RcTnT_1–43Δ	RcTnT_44–73Δ
α-MHC
b (s⁻¹)	18.14 ± 0.62	18.38 ± 1.10	17.46 ± 0.43
k_tr (s⁻¹)	7.32 ± 0.17	7.25 ± 0.31	6.79 ± 0.29
c (s⁻¹)	21.41 ± 0.83	20.60 ± 1.53	20.14 ± 0.07
β-MHC
b (s⁻¹)	7.55 ± 0.34^a	7.84 ± 0.17^a	7.53 ± 0.22^a
k_tr (s⁻¹)	4.15 ± 0.11^a	4.38 ± 0.08^a	4.40 ± 0.11^a
c (s⁻¹)	10.72 ± 0.40^a	10.70 ± 0.35^a	11.68 ± 0.30^a

The SL of the muscle fiber was set to 2.3 µm. b and c were estimated as described previously (Ford et al., 2010). k_tr was estimated using a rapid slack/restretch protocol (Brenner and Eisenberg, 1986). Number of determinations was at least 11 for each group. Values are reported as mean ± SEM.

P < 0.001 when compared to the corresponding groups in α-MHC fibers.

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