Table 1. Parameters of activation... | Rockefeller University Press

Table 1.

Parameters of activation

Condition	−β4 Peptide			+β4 Peptide			P-value (−β4 vs. +β4)
	V_1/2	k	G_max	V_1/2	k	G_max	V_1/2	k	G_max
	mV	mV	nS	mV	mV	nS
WT − ATX (n = 6, 5)	−11.2 ± 0.7	8.7 ± 0.2	28.1 ± 3.3	−13.5 ± 0.5	8.1 ± 0.3	38.5 ± 10.9	<0.05	0.1	0.3
WT + ATX (n = 6, 5)	−16.5 ± 0.9	8.4 ± 0.1	33.0 ± 4.2	−20.5 ± 1.1	7.8 ± 0.5	40.1 ± 10.9	<0.05	0.2	0.5
CW − ATX (n = 5, 6)	−10.9 ± 0.8	10.0 ± 0.3	24.7 ± 7.3	−9.4 ± 1.0	11.7 ± 0.3	20.2 ± 6.4	0.3	<0.005	0.7
CW + ATX (n = 5, 6)	−35.6 ± 2.1	5.6 ± 0.5	45.7 ± 10.1	−34.9 ± 1.4	7.4 ± 0.5	31.2 ± 10.2	0.8	<0.05	0.5

Condition	−β4 Peptide			+β4 Peptide			P-value (−β4 vs. +β4)
	V_1/2	k	G_max	V_1/2	k	G_max	V_1/2	k	G_max
	mV	mV	nS	mV	mV	nS
WT − ATX (n = 6, 5)	−11.2 ± 0.7	8.7 ± 0.2	28.1 ± 3.3	−13.5 ± 0.5	8.1 ± 0.3	38.5 ± 10.9	<0.05	0.1	0.3
WT + ATX (n = 6, 5)	−16.5 ± 0.9	8.4 ± 0.1	33.0 ± 4.2	−20.5 ± 1.1	7.8 ± 0.5	40.1 ± 10.9	<0.05	0.2	0.5
CW − ATX (n = 5, 6)	−10.9 ± 0.8	10.0 ± 0.3	24.7 ± 7.3	−9.4 ± 1.0	11.7 ± 0.3	20.2 ± 6.4	0.3	<0.005	0.7
CW + ATX (n = 5, 6)	−35.6 ± 2.1	5.6 ± 0.5	45.7 ± 10.1	−34.9 ± 1.4	7.4 ± 0.5	31.2 ± 10.2	0.8	<0.05	0.5