Comparison of HC and GJC function
| Cx26 | HC | HC + DTT | GJC |
| WT | + (349 pS) | + | + (150 pS) |
| D50N | + (167 pS) | + | − |
| D50A | + (162 pS) | + | − |
| D50C | + (172 pS) | + | − |
| K61A | − | − | + (210 pS) |
| K61C | − | − | + (200 pS) |
| Q48A | + (ND) | + | + (151 pS) |
| Q48C | − | + | + (154 pS) |
| Q48A + D50A | + (ND) | + | + |
| Q48C + D50C | − | + | +/− |
| Cx26 | HC | HC + DTT | GJC |
| WT | + (349 pS) | + | + (150 pS) |
| D50N | + (167 pS) | + | − |
| D50A | + (162 pS) | + | − |
| D50C | + (172 pS) | + | − |
| K61A | − | − | + (210 pS) |
| K61C | − | − | + (200 pS) |
| Q48A | + (ND) | + | + (151 pS) |
| Q48C | − | + | + (154 pS) |
| Q48A + D50A | + (ND) | + | + |
| Q48C + D50C | − | + | +/− |
GJC, GJ channel; HC, hemichannel; ND, not determined because of low expression.