Table 1. Activation and coupling... | Rockefeller University Press

Table 1.

Activation and coupling energies of Cx26 WT, Q48A, D50A, and Q48A + D50A hemichannels

Cx26	z	V_1/2	ΔG⁰	Δ(ΔG⁰)	ΔG⁰_coupling
		mV	kcal/mol
WT
(0 mM Ca²⁺)	1.2	−61.8	−1.65
(2 mM Ca²⁺)	2.8	1.0	0.07
Q48A
(0 mM Ca²⁺)	1.3	−32.8	−0.95	0.70
(2 mM Ca²⁺)	1.0	15.9	0.34	−0.27
D50A
(0 mM Ca²⁺)	0.9	−6.4	−0.14	1.51
(2 mM Ca²⁺)	1.1	−1.1	−0.03	0.10
Q48A + D50A
(0 mM Ca²⁺)	1.1	−4.4	−0.11	1.54	0.67
(2 mM Ca²⁺)	1.5	2.2	0.08	0.01	0.17

Cx26	z	V_1/2	ΔG⁰	Δ(ΔG⁰)	ΔG⁰_coupling
		mV	kcal/mol
WT
(0 mM Ca²⁺)	1.2	−61.8	−1.65
(2 mM Ca²⁺)	2.8	1.0	0.07
Q48A
(0 mM Ca²⁺)	1.3	−32.8	−0.95	0.70
(2 mM Ca²⁺)	1.0	15.9	0.34	−0.27
D50A
(0 mM Ca²⁺)	0.9	−6.4	−0.14	1.51
(2 mM Ca²⁺)	1.1	−1.1	−0.03	0.10
Q48A + D50A
(0 mM Ca²⁺)	1.1	−4.4	−0.11	1.54	0.67
(2 mM Ca²⁺)	1.5	2.2	0.08	0.01	0.17

Empty cells indicate that the information is not applicable.