Scheme 4 parameters and fitted values from simulated data
| Parameter | Quantity | Units | Fit (mean ± SEM) | p-value |
| ΔqL | 0.3a | eo | 0.305 ± 0.002 (n = 10) | 0.063 |
| ΔGL | 350a | meV | — | |
| ΔqJ1 | 0.2b | eo | — | |
| ΔGJ1 | 121c | meV | — | |
| ΔqJ2 | 0.38d | eo | — | |
| ΔGJ2 | 157c | meV | — | |
| ΔnK1 | 1.0 | — | — | |
| ΔGK1 | 79e | meV | — | |
| ΔnK2 | 1.0 | — | — | |
| ΔGK2 | 29e | meV | — | |
| ΔWC | −53a | meV | −52.5 ± 0.7 (n = 10) | 0.417 |
| ΔWD | −81a | meV | −78.6 ± 0.7 (n = 10) | 0.009 |
| ΔWC + ΔWE | −75a | meV | −69.6 ± 2.3 (n = 10) | 0.044 |
| ΔWF | 20e | meV | — | |
| ΔWG | −195c | meV | — | |
| αL | 0.1a | kHz | — | |
| αJ | 10a | kHz | — | |
| αK | 10a | kHz | — | |
| ΔqT | 2.62f | eo | 2.56 ± 0.03 (n = 10) | 0.055 |
| gL | 50 | pS | — |
| Parameter | Quantity | Units | Fit (mean ± SEM) | p-value |
| ΔqL | 0.3a | eo | 0.305 ± 0.002 (n = 10) | 0.063 |
| ΔGL | 350a | meV | — | |
| ΔqJ1 | 0.2b | eo | — | |
| ΔGJ1 | 121c | meV | — | |
| ΔqJ2 | 0.38d | eo | — | |
| ΔGJ2 | 157c | meV | — | |
| ΔnK1 | 1.0 | — | — | |
| ΔGK1 | 79e | meV | — | |
| ΔnK2 | 1.0 | — | — | |
| ΔGK2 | 29e | meV | — | |
| ΔWC | −53a | meV | −52.5 ± 0.7 (n = 10) | 0.417 |
| ΔWD | −81a | meV | −78.6 ± 0.7 (n = 10) | 0.009 |
| ΔWC + ΔWE | −75a | meV | −69.6 ± 2.3 (n = 10) | 0.044 |
| ΔWF | 20e | meV | — | |
| ΔWG | −195c | meV | — | |
| αL | 0.1a | kHz | — | |
| αJ | 10a | kHz | — | |
| αK | 10a | kHz | — | |
| ΔqT | 2.62f | eo | 2.56 ± 0.03 (n = 10) | 0.055 |
| gL | 50 | pS | — |
Parameters adopted from Horrigan and Aldrich (2002).
Parameters adopted from Pantazis et al. (2010).
Parameters obtained from simultaneous fits to Q-V and G-V curves at [Ca2+] = 10−3 and 70 µM obtained from the HA model.
= ΔqJ − ΔqJ1, where ΔqJ = 0.58 eo is adopted from Horrigan and Aldrich (2002).
Parameters adopted from Sweet and Cox (2008).
ΔqT = ΔqL + 4(ΔqJ1 + ΔqJ2).