Table 3.

Rules for extracting Z from linkage diagrams

Expression Interpretation 
(…) CPF unit 
(KCPF = 1 + K 
(KECPF = 1 + KE 
(J)(KCPF = (1 + J)(1 + K
((A)K(B)) CPF = (CPFA) + K(CPFB
((A)K(B)K2(C)) CPF = (CPFA) + K(CPFB) + K2(CPFC
(K[F]) CPF = f(K1, K2, K3,…F1, F2, F3,…) 
(K[F])() CPF(−) = 1 
(K[F])(+) CPF(+) = K1K2K3F1F2F3… 
Expression Interpretation 
(…) CPF unit 
(KCPF = 1 + K 
(KECPF = 1 + KE 
(J)(KCPF = (1 + J)(1 + K
((A)K(B)) CPF = (CPFA) + K(CPFB
((A)K(B)K2(C)) CPF = (CPFA) + K(CPFB) + K2(CPFC
(K[F]) CPF = f(K1, K2, K3,…F1, F2, F3,…) 
(K[F])() CPF(−) = 1 
(K[F])(+) CPF(+) = K1K2K3F1F2F3… 

J and K are particle equilibrium constants; C and F are allosteric factors; A, B, and C represent limiting states; and variables in bold type (K, F) represent composite particles.

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