Table 2. Fractional magnitudes of time... | Rockefeller University Press

Table 2.

Fractional magnitudes of time constants for ionic current, and fluorescence during the onset of SI in the presence of TTX

Channel variant (measured parameter)	A_F	A_I	A_S	C	n
WT (I) 70 nM TTX	0.12 ± 0.02	0.07 ± 0.03	0.50 ± 0.07	0.31 ± 0.09	7
WT (I) 200 nM TTX	0.12 ± 0.03	0.06 ± 0.02^a	0.42 ± 0.10	0.40 ± 0.10	11
DI (F) + 200 nM TTX	0.13 ± 0.06	0.05 ± 0.02^a	0.24 ± 0.07	0.59 ± 0.06^a	6
DII (F) + 200 nM TTX	0.13 ± 0.04	0.11 ± 0.04^a	0.22 ± 0.05	0.54 ± 0.03^a	6
DIII (F) + 200 nM TTX	0.39 ± 0.05	0.05 ± 0.03	0.27 ± 0.07	0.30 ± 0.08	6
DIV (F) + 200 nM TTX	0.27 ± 0.05	0.01 ± 0.00	0.09 ± 0.03	0.63 ± 0.08	5

Channel variant (measured parameter)	A_F	A_I	A_S	C	n
WT (I) 70 nM TTX	0.12 ± 0.02	0.07 ± 0.03	0.50 ± 0.07	0.31 ± 0.09	7
WT (I) 200 nM TTX	0.12 ± 0.03	0.06 ± 0.02^a	0.42 ± 0.10	0.40 ± 0.10	11
DI (F) + 200 nM TTX	0.13 ± 0.06	0.05 ± 0.02^a	0.24 ± 0.07	0.59 ± 0.06^a	6
DII (F) + 200 nM TTX	0.13 ± 0.04	0.11 ± 0.04^a	0.22 ± 0.05	0.54 ± 0.03^a	6
DIII (F) + 200 nM TTX	0.39 ± 0.05	0.05 ± 0.03	0.27 ± 0.07	0.30 ± 0.08	6
DIV (F) + 200 nM TTX	0.27 ± 0.05	0.01 ± 0.00	0.09 ± 0.03	0.63 ± 0.08	5

τ_F, τ_I, and τ_S and channel variant abbreviations are as in Table 1. p-values were calculated to evaluate differences between WT signals and those with TTX.

Significant differences, P < 0.05.

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