Table 3. Boltzmann fits to F-V curves... | Rockefeller University Press

Table 3.

Boltzmann fits to F-V curves

Channel variant	A₁	B₁	C₁	A₂	B₂	C₂	D
L689I DI	0.53	0.01677	15.01	2.81	0.1601	137.7	−2.04
L689I DII	0.16	0.00003	6.07	1.04	0.0707	28.4	−0.19
L689I DIII	0.74	0.00001	6.58	0.41	0.0002	12.9	−0.19
L689I DIV	0.21	0.000001	4.23	0.87	0.0075	18.0	−0.11

Channel variant	A₁	B₁	C₁	A₂	B₂	C₂	D
L689I DI	0.53	0.01677	15.01	2.81	0.1601	137.7	−2.04
L689I DII	0.16	0.00003	6.07	1.04	0.0707	28.4	−0.19
L689I DIII	0.74	0.00001	6.58	0.41	0.0002	12.9	−0.19
L689I DIV	0.21	0.000001	4.23	0.87	0.0075	18.0	−0.11

For F-V curves, two Boltzmann functions fit the curve well: $\sum_{i = 1}^{2} \frac{A_{i}}{1 + B_{i} e^{- V_{m} / C_{i}}} + D .$ In each case, only one Boltzmann described voltage dependence above −100 mV. To derive the steady-state activated probability for modeling purposes, A was set to 1 and D to 0. The values predicted by this normalized function were used to calculate the steady-state occupancy. Channel variant abbreviations as in Table 1.

[ViewLarge]

This Feature Is Available To Subscribers Only