Table 3. Transition rates between states... | Rockefeller University Press

Table 3.

Transition rates between states at different [Ca²⁺]_cyt

Transitions	[Ca²⁺]_cyt
	0.25 µM	1 µM	10 µM	200 µM	10–500^a µM
C1→C2	16	92	99	115	117
C2→C1	7	38	23	13	34
C2→O1	20^b	222	792	613	713
O1→C2	5,760^b	1,674	634	834	842
C2→C3	154	—	—	—	—
C3→C2	550	—	—	—	—
C2→O2	—	—	—	—	—
O2→C2	—	—	—	—	—
O1→O2	—	1,665	277	632	522
O2→O1	—	281	124	247	147
O2→C3	2,235	87	651^c	616^c	629^c
C3→O2	156	1,133	2,599^c	2,654^c	2,976^c
O2→O3	521	26	523	638	606
O3→O2	627	65	521	505	574
O3→O4	—	—	20	22	38
O4→O3	—	—	84	92	94

Transitions	[Ca²⁺]_cyt
	0.25 µM	1 µM	10 µM	200 µM	10–500^a µM
C1→C2	16	92	99	115	117
C2→C1	7	38	23	13	34
C2→O1	20^b	222	792	613	713
O1→C2	5,760^b	1,674	634	834	842
C2→C3	154	—	—	—	—
C3→C2	550	—	—	—	—
C2→O2	—	—	—	—	—
O2→C2	—	—	—	—	—
O1→O2	—	1,665	277	632	522
O2→O1	—	281	124	247	147
O2→C3	2,235	87	651^c	616^c	629^c
C3→O2	156	1,133	2,599^c	2,654^c	2,976^c
O2→O3	521	26	523	638	606
O3→O2	627	65	521	505	574
O3→O4	—	—	20	22	38
O4→O3	—	—	84	92	94

State transitions directly correspond to those of the top-ranked models in Table 2. Units are s⁻¹ or µM⁻¹s⁻¹, as appropriate.

Global fitting across the high [Ca²⁺]_cyt range (10–500 µM).

Rates for unliganded gating transitions.

Flicker transitions from the Ca²⁺-bound open state.