Table 2.

Properties of simulated APs in a model of the hippocampal CA1 neuron

AP Property CSI CSI + OSI 
bAP peak (mV) −47 −33 
Latencya (ms) 173 143 
Kv4.2 availability (first/last AP)b 0.87/0.21 (0.25) 0.87/0.10 (0.11) 
Peak (mV) 16.2/12.3 16.6/1.4 
 (0.76) (0.09) 
AHP (mV) −64.0/−56.7 −59.5/−50.3 
 (0.88) (0.85) 
ISI (ms) 11.3/10.5 11.4/11.3c 
 (0.95) (0.99) 
Width50 (ms) 0.56/0.79 0.53/1.22 
 (1.42) (2.30) 
AP Property CSI CSI + OSI 
bAP peak (mV) −47 −33 
Latencya (ms) 173 143 
Kv4.2 availability (first/last AP)b 0.87/0.21 (0.25) 0.87/0.10 (0.11) 
Peak (mV) 16.2/12.3 16.6/1.4 
 (0.76) (0.09) 
AHP (mV) −64.0/−56.7 −59.5/−50.3 
 (0.88) (0.85) 
ISI (ms) 11.3/10.5 11.4/11.3c 
 (0.95) (0.99) 
Width50 (ms) 0.56/0.79 0.53/1.22 
 (1.42) (2.30) 
a

In response to a 40-pA current injection.

b

Comparing the channel availability corresponding to the first and last AP (first/last). For all properties, the number in parenthesis is the fold change between the first and last AP.

c

Although the ISI ratio indicates no change between the first and the last interval, the time course shows slight rising and falling of the ISI during the AP train.

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