Properties of simulated APs in a model of the hippocampal CA1 neuron
| AP Property | CSI | CSI + OSI |
| bAP peak (mV) | −47 | −33 |
| Latencya (ms) | 173 | 143 |
| Kv4.2 availability (first/last AP)b | 0.87/0.21 (0.25) | 0.87/0.10 (0.11) |
| Peak (mV) | 16.2/12.3 | 16.6/1.4 |
| (0.76) | (0.09) | |
| AHP (mV) | −64.0/−56.7 | −59.5/−50.3 |
| (0.88) | (0.85) | |
| ISI (ms) | 11.3/10.5 | 11.4/11.3c |
| (0.95) | (0.99) | |
| Width50 (ms) | 0.56/0.79 | 0.53/1.22 |
| (1.42) | (2.30) |
| AP Property | CSI | CSI + OSI |
| bAP peak (mV) | −47 | −33 |
| Latency | 173 | 143 |
| Kv4.2 availability (first/last AP) | 0.87/0.21 (0.25) | 0.87/0.10 (0.11) |
| Peak (mV) | 16.2/12.3 | 16.6/1.4 |
| (0.76) | (0.09) | |
| AHP (mV) | −64.0/−56.7 | −59.5/−50.3 |
| (0.88) | (0.85) | |
| ISI (ms) | 11.3/10.5 | 11.4/11.3 |
| (0.95) | (0.99) | |
| Width50 (ms) | 0.56/0.79 | 0.53/1.22 |
| (1.42) | (2.30) |
In response to a 40-pA current injection.
Comparing the channel availability corresponding to the first and last AP (first/last). For all properties, the number in parenthesis is the fold change between the first and last AP.
Although the ISI ratio indicates no change between the first and the last interval, the time course shows slight rising and falling of the ISI during the AP train.
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