Table 2. Effect of [Ca 2 ] C on... | Rockefeller University Press

Table 2.

Effect of [Ca²⁺]_C on activation of the RYR2 channel by ATP

[Ca²⁺]_C	$P_{O}^{max}$	EC₅₀ for ATP	n_H
nM		mM
100	0.051^a	0.549^a	1.97 ± 0.21
180	0.541 ± 0.037	0.529 ± 0.076	1.97 ± 0.21
250	0.700 ± 0.061	0.499 ± 0.081	1.97 ± 0.21
330	0.782 ± 0.037	0.437 ± 0.044	1.97 ± 0.21
410	0.946 ± 0.029	0.089 ± 0.006	1.97 ± 0.21

[Ca²⁺]_C	$P_{O}^{max}$	EC₅₀ for ATP	n_H
nM		mM
100	0.051^a	0.549^a	1.97 ± 0.21
180	0.541 ± 0.037	0.529 ± 0.076	1.97 ± 0.21
250	0.700 ± 0.061	0.499 ± 0.081	1.97 ± 0.21
330	0.782 ± 0.037	0.437 ± 0.044	1.97 ± 0.21
410	0.946 ± 0.029	0.089 ± 0.006	1.97 ± 0.21

[Ca²⁺]_L was 1 mM.

Fixed parameter.