Table 1. Effect of [Ca 2 ] L on... | Rockefeller University Press

Table 1.

Effect of [Ca²⁺]_L on activation of the RYR2 channel by ATP

[Ca²⁺]_L	$P_{O}^{max}$	EC₅₀ for ATP	n_H
mM		mM
0.005	0.0048 ± 0.0007	9.9 ± 1.8	2.51 ± 0.82
1	0.051 ± 0.017	0.549 ± 0.034	1.90 ± 0.17
8	0.290 ± 0.027	0.549 ± 0.034	1.90 ± 0.17
15	0.574 ± 0.024	0.549 ± 0.034	1.90 ± 0.17
26	0.662 ± 0.029	0.549 ± 0.034	1.90 ± 0.17
53	1.000 ± 0.049	0.549 ± 0.034	1.90 ± 0.17

[Ca²⁺]_L	$P_{O}^{max}$	EC₅₀ for ATP	n_H
mM		mM
0.005	0.0048 ± 0.0007	9.9 ± 1.8	2.51 ± 0.82
1	0.051 ± 0.017	0.549 ± 0.034	1.90 ± 0.17
8	0.290 ± 0.027	0.549 ± 0.034	1.90 ± 0.17
15	0.574 ± 0.024	0.549 ± 0.034	1.90 ± 0.17
26	0.662 ± 0.029	0.549 ± 0.034	1.90 ± 0.17
53	1.000 ± 0.049	0.549 ± 0.034	1.90 ± 0.17

[Ca²⁺]_C was 100 nM.