Known acetylation sites on UniProt among ETC and TCA proteins in the mouse and human heart
| Protein name | Species | UniProt accession | Acetylation site(s) |
| Aconitase | Human | Q99798 | K50, K573, K605 |
| Mouse | Q99KI0 | K50 | |
| Acyl carrier protein | Human | O14561 | K92 |
| ATP synthase protein 8 | Mouse | P03930 | K54 |
| ATP synthase subunit b | Human | P24539 | K221, K233 |
| Mouse | Q9CQQ7 | K115, K131, K162, K188, K221, K225, K233 | |
| ATP synthase subunit d | Human | O75947 | K85, K95, K117, K149 |
| Mouse | Q9DCX2 | K63, K78, K85, K99, K117, K149 | |
| ATP synthase subunit f | Human | P56134 | A2 |
| ATP synthase subunit g | Human | O75964 | A2, K24 |
| Mouse | Q9CPQ8 | K54, K66 | |
| ATP synthase subunit γ | Human | P36542 | K55, K154, K197 |
| Mouse | Q91VR2 | K79, K90, K115 | |
| ATP synthase subunit O | Human | P48047 | K54, K60, K70, K162, K172, K192 |
| Mouse | Q9DB20 | K60, K70, K158, K162, K172, K176, K192 | |
| ATP synthase subunit α | Human | P25705 | K161, K261, K305, K434, K498, K506, K539 |
| Mouse | Q03265 | K132, K230, K239, K261, K305, K427, K498, K531, K539 | |
| ATP synthase subunit β | Human | P06576 | K133, K198, K426, K485 |
| Mouse | P56480 | K133, K259, K522 | |
| ATP synthase-coupling factor 6 | Human | P18859 | K41, K46, K99, K105 |
| Mouse | P97450 | K84, K99 | |
| Citrate synthase | Human | O75390 | K327, K366, K375, K382, K393 |
| Cytochrome b-c1 complex subunit 1 | Human | P31930 | K111 |
| Cytochrome b-c1 complex subunit 2 | Mouse | Q9DB77 | K159, K250 |
| Cytochrome b-c1 complex subunit 6 | Human | P07919 | K85 |
| Mouse | P99028 | K40 | |
| Cytochrome b-c1 complex subunit 7 | Human | P14927 | K78 |
| Cytochrome c oxidase polypeptide VIc | Mouse | Q9CPQ1 | K61 |
| Cytochrome c oxidase subunit 4 isoform 1 | Human | P13073 | K53, K60 |
| Cytochrome c oxidase subunit 5B | Human | P10606 | K121 |
| Cytochrome c oxidase subunit 7A-related | Human | O14548 | K69 |
| Dihydrolipoyl dehydrogenase | Human | P09622 | K143, K267, K320, K410, K417, K420 |
| Mouse | O08749 | K127 | |
| Fumarate hydratase | Human | P07954 | K66, K80, K94, K256, K292 |
| Mouse | P97807 | K63, K112, K474 | |
| Isocitrate dehydrogenase subunit β | Human | O43837 | K146, K199, K374 |
| Isocitric dehydrogenase subunit α | Human | P50213 | K343 |
| Malate dehydrogenase | Human | P40926 | K165, K185, K301, K307, K314, K329, K335 |
| Mouse | P08249 | K157, K239, K314 | |
| NADH-ubiquinone oxidoreductase 13-kD A subunit | Mouse | P52503 | K112 |
| NADH-ubiquinone oxidoreductase 13-kD B subunit | Mouse | Q9CPP6 | K36, K46, K98 |
| NADH-ubiquinone oxidoreductase 39-kD subunit | Mouse | Q9DC69 | K370 |
| NADH-ubiquinone oxidoreductase 42-kD subunit | Mouse | Q99LC3 | K122, K181, K242, K350 |
| NADH-ubiquinone oxidoreductase 51-kD subunit | Mouse | Q91YT0 | K81, K104, K375 |
| NADH-ubiquinone oxidoreductase 75-kD subunit | Mouse | Q91VD9 | K84 |
| NADH-ubiquinone oxidoreductase B12 subunit | Mouse | Q9CQZ6 | K29, K40 |
| NADH-ubiquinone oxidoreductase B22 subunit | Human | Q9Y6M9 | A2 |
| NADH-ubiquinone oxidoreductase B8 subunit | Human | O43678 | A2 |
| Mouse | Q9CQ75 | K64, K75 | |
| NADH-ubiquinone oxidoreductase MLRQ subunit | Mouse | Q62425 | K56 |
| NADH-ubiquinone oxidoreductase subunit B14.5b | Human | O95298 | K114 |
| NADH-ubiquinone oxidoreductase subunit B17.2 | Mouse | Q7TMF3 | K43, K47 |
| Succinate dehydrogenase flavoprotein subunit | Human | P31040 | K179, K335, K541, K547, K608 |
| Mouse | Q8K2B3 | K179, K423, K485, K498, K538, K547 | |
| Succinyl-CoA synthetase β A chain | Human | Q9P2R7 | K78, K143 |
| Succinyl-CoA synthetase β G chain | Human | Q96I99 | K73, K227, K291, K338 |
| Succinyl-CoA synthetase subunit α | Human | P53597 | K54 |
| Protein name | Species | UniProt accession | Acetylation site(s) |
| Aconitase | Human | Q99798 | K50, K573, K605 |
| Mouse | Q99KI0 | K50 | |
| Acyl carrier protein | Human | O14561 | K92 |
| ATP synthase protein 8 | Mouse | P03930 | K54 |
| ATP synthase subunit b | Human | P24539 | K221, K233 |
| Mouse | Q9CQQ7 | K115, K131, K162, K188, K221, K225, K233 | |
| ATP synthase subunit d | Human | O75947 | K85, K95, K117, K149 |
| Mouse | Q9DCX2 | K63, K78, K85, K99, K117, K149 | |
| ATP synthase subunit f | Human | P56134 | A2 |
| ATP synthase subunit g | Human | O75964 | A2, K24 |
| Mouse | Q9CPQ8 | K54, K66 | |
| ATP synthase subunit γ | Human | P36542 | K55, K154, K197 |
| Mouse | Q91VR2 | K79, K90, K115 | |
| ATP synthase subunit O | Human | P48047 | K54, K60, K70, K162, K172, K192 |
| Mouse | Q9DB20 | K60, K70, K158, K162, K172, K176, K192 | |
| ATP synthase subunit α | Human | P25705 | K161, K261, K305, K434, K498, K506, K539 |
| Mouse | Q03265 | K132, K230, K239, K261, K305, K427, K498, K531, K539 | |
| ATP synthase subunit β | Human | P06576 | K133, K198, K426, K485 |
| Mouse | P56480 | K133, K259, K522 | |
| ATP synthase-coupling factor 6 | Human | P18859 | K41, K46, K99, K105 |
| Mouse | P97450 | K84, K99 | |
| Citrate synthase | Human | O75390 | K327, K366, K375, K382, K393 |
| Cytochrome b-c1 complex subunit 1 | Human | P31930 | K111 |
| Cytochrome b-c1 complex subunit 2 | Mouse | Q9DB77 | K159, K250 |
| Cytochrome b-c1 complex subunit 6 | Human | P07919 | K85 |
| Mouse | P99028 | K40 | |
| Cytochrome b-c1 complex subunit 7 | Human | P14927 | K78 |
| Cytochrome c oxidase polypeptide VIc | Mouse | Q9CPQ1 | K61 |
| Cytochrome c oxidase subunit 4 isoform 1 | Human | P13073 | K53, K60 |
| Cytochrome c oxidase subunit 5B | Human | P10606 | K121 |
| Cytochrome c oxidase subunit 7A-related | Human | O14548 | K69 |
| Dihydrolipoyl dehydrogenase | Human | P09622 | K143, K267, K320, K410, K417, K420 |
| Mouse | O08749 | K127 | |
| Fumarate hydratase | Human | P07954 | K66, K80, K94, K256, K292 |
| Mouse | P97807 | K63, K112, K474 | |
| Isocitrate dehydrogenase subunit β | Human | O43837 | K146, K199, K374 |
| Isocitric dehydrogenase subunit α | Human | P50213 | K343 |
| Malate dehydrogenase | Human | P40926 | K165, K185, K301, K307, K314, K329, K335 |
| Mouse | P08249 | K157, K239, K314 | |
| NADH-ubiquinone oxidoreductase 13-kD A subunit | Mouse | P52503 | K112 |
| NADH-ubiquinone oxidoreductase 13-kD B subunit | Mouse | Q9CPP6 | K36, K46, K98 |
| NADH-ubiquinone oxidoreductase 39-kD subunit | Mouse | Q9DC69 | K370 |
| NADH-ubiquinone oxidoreductase 42-kD subunit | Mouse | Q99LC3 | K122, K181, K242, K350 |
| NADH-ubiquinone oxidoreductase 51-kD subunit | Mouse | Q91YT0 | K81, K104, K375 |
| NADH-ubiquinone oxidoreductase 75-kD subunit | Mouse | Q91VD9 | K84 |
| NADH-ubiquinone oxidoreductase B12 subunit | Mouse | Q9CQZ6 | K29, K40 |
| NADH-ubiquinone oxidoreductase B22 subunit | Human | Q9Y6M9 | A2 |
| NADH-ubiquinone oxidoreductase B8 subunit | Human | O43678 | A2 |
| Mouse | Q9CQ75 | K64, K75 | |
| NADH-ubiquinone oxidoreductase MLRQ subunit | Mouse | Q62425 | K56 |
| NADH-ubiquinone oxidoreductase subunit B14.5b | Human | O95298 | K114 |
| NADH-ubiquinone oxidoreductase subunit B17.2 | Mouse | Q7TMF3 | K43, K47 |
| Succinate dehydrogenase flavoprotein subunit | Human | P31040 | K179, K335, K541, K547, K608 |
| Mouse | Q8K2B3 | K179, K423, K485, K498, K538, K547 | |
| Succinyl-CoA synthetase β A chain | Human | Q9P2R7 | K78, K143 |
| Succinyl-CoA synthetase β G chain | Human | Q96I99 | K73, K227, K291, K338 |
| Succinyl-CoA synthetase subunit α | Human | P53597 | K54 |
Proteins from ETC complexes and the TCA cycle were experimentally determined from mouse and human heart mitochondria. The PTM information of the protein was retrieved from UniProt. The referenced acetylation sites were identified from their respective species but may have originated from different tissues other than the heart (e.g. mouse liver, human HeLa cells). Tissue-specific PTM distribution is a matter of intense investigation.