Table 1.

τ of deactivation at different voltages for KCNQ1 S1 mutants

Construct Tau at −80 mV Tau at −100 mV Tau at −120 mV 
WT KCNQ1 131 ± 31 104 ± 3 82 ± 14 
KCNQ1 S140G 2,240 ± 160a 1,090 ± 71a 666 ± 110a 
KCNQ1 V141M 153 ± 18 101 ± 32 80 ± 28 
Construct Tau at −80 mV Tau at −100 mV Tau at −120 mV 
WT KCNQ1 131 ± 31 104 ± 3 82 ± 14 
KCNQ1 S140G 2,240 ± 160a 1,090 ± 71a 666 ± 110a 
KCNQ1 V141M 153 ± 18 101 ± 32 80 ± 28 

Data presented as mean tau of deactivation from exponential fit ± SEM (n = 4–6).

a

The tau of deactivation is significantly different from WT at the indicated voltage.

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