Effects of voltage on exponential components at 20°C
| Exp. | 40 mV | 100 mV | ||
| τa | Areab | τ | Area | |
| ms | ms | |||
| EC1 | 0.25 ± 0.02 | 0.35 ± 0.02 | 0.23 ± 0.01 | 0.44 ± 0.02** |
| EC2 | 1.91 ± 0.26 | 0.36 ± 0.02 | 1.13 ± 0.13* | 0.37 ± 0.02 |
| EC3 | 10.8 ± 2.47 | 0.24 ± 0.02 | 4.41 ± 1.05** | 0.16 ± 0.02 |
| EC4 | 57.9 ± 17.0 | 0.055 ± 0.014 | 19.2 ± 4.12** | 0.025 ± 0.006 |
| EC5 | 4,227 ± 2,067 | 0.0041 ± 0.0029 | 2,428 ± 896 | 0.00035 ± 0.00008* |
| EO1 | 0.49 ± 0.06 | 0.58 ± 0.03 | 0.87 ± 0.08** | 0.56 ± 0.04 |
| EO2 | 1.25 ± 0.21 | 0.42 ± 0.03 | 2.27 ± 0.27** | 0.44 ± 0.04 |
| Exp. | 40 mV | 100 mV | ||
| τa | Areab | τ | Area | |
| ms | ms | |||
| EC1 | 0.25 ± 0.02 | 0.35 ± 0.02 | 0.23 ± 0.01 | 0.44 ± 0.02** |
| EC2 | 1.91 ± 0.26 | 0.36 ± 0.02 | 1.13 ± 0.13* | 0.37 ± 0.02 |
| EC3 | 10.8 ± 2.47 | 0.24 ± 0.02 | 4.41 ± 1.05** | 0.16 ± 0.02 |
| EC4 | 57.9 ± 17.0 | 0.055 ± 0.014 | 19.2 ± 4.12** | 0.025 ± 0.006 |
| EC5 | 4,227 ± 2,067 | 0.0041 ± 0.0029 | 2,428 ± 896 | 0.00035 ± 0.00008* |
| EO1 | 0.49 ± 0.06 | 0.58 ± 0.03 | 0.87 ± 0.08** | 0.56 ± 0.04 |
| EO2 | 1.25 ± 0.21 | 0.42 ± 0.03 | 2.27 ± 0.27** | 0.44 ± 0.04 |
All values are means ± SEM for two open and five closed exponential components (EO1–EO2 and EC1–EC5, respectively) fitted by the maximum likelihood method to dwell-time histograms from eight single-channel patches at 40 and 100 mV and 20°C. The mean values have been compared using the Wilcoxon matched pairs test (*, P < 0.05; **, P < 0.01). These averaged values should not be used to calculate Po and mean open- and mean closed-time values. Rather, the separate values should be calculated for each channel and then averaged.
Mean dwell times for each exponential component.
Relative areas for each exponential component indicating its contribution to the total number of closed or open events.