Table III.

CoV of parameter estimates

Model parameter CoV WT-cTnT cTnTS199E/T204E 
 RD NLRD p-value RD NLRD p-value 
b CoV 0.0196 ± 0.0004 0.0071 ± 0.0005 2.8 × 10−9 0.0275 ± 0.0027 0.0087 ± 0.0005 0.0001 
c CoV 0.0144 ± 0.0003 0.0061 ± 0.0003 3.6 × 10−9 0.0181 ± 0.0009 0.0079 ± 0.0004 8.3 × 10−6 
γ CoV — 0.0092 ± 0.0006 — — 0.0005 ± 0.0005 — 
Model parameter CoV WT-cTnT cTnTS199E/T204E 
 RD NLRD p-value RD NLRD p-value 
b CoV 0.0196 ± 0.0004 0.0071 ± 0.0005 2.8 × 10−9 0.0275 ± 0.0027 0.0087 ± 0.0005 0.0001 
c CoV 0.0144 ± 0.0003 0.0061 ± 0.0003 3.6 × 10−9 0.0181 ± 0.0009 0.0079 ± 0.0004 8.3 × 10−6 
γ CoV — 0.0092 ± 0.0006 — — 0.0005 ± 0.0005 — 

In all cases, the CoV of the parameter estimates were <5%, suggesting that these parameters were estimated with a high degree of confidence. Estimates are reported as mean ± SEM. CoV were less in the NLRD model, suggesting that these parameters were estimated with an even higher degree of confidence than those estimated using the RD model.

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