TABLE II.

Thermodynamic parameters for the opening transition for heterotetramers with different stoichiometries of ILT mutations

Shakerb zα zβ ΔG ΔHa TΔS 
 e0 e0 kCal/mol kCal/mol kCal/mol 
 0.51 −0.6 −30.2 −29.6 
1ILT/3neu 0.35 −0.4 13.3 13.7 
1ILT/3wt 0.39 −0.5 18.5 19.0 
2ILT/2wt 0.34 6.8 6.8 
3ILT/1wt 0.30 0.4 10.9 11.3 
4ILT 0.38 1.1 8.1 
Shakerb zα zβ ΔG ΔHa TΔS 
 e0 e0 kCal/mol kCal/mol kCal/mol 
 0.51 −0.6 −30.2 −29.6 
1ILT/3neu 0.35 −0.4 13.3 13.7 
1ILT/3wt 0.39 −0.5 18.5 19.0 
2ILT/2wt 0.34 6.8 6.8 
3ILT/1wt 0.30 0.4 10.9 11.3 
4ILT 0.38 1.1 8.1 
a

Computed at V = 0.

b

Rodriguez and Bezanilla, 1996.

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