TABLE I.

Activation energy (Ea) calculated from Arrhenius plots of the rate of activation (f)/deactivation (b) (slow, fast, and weighted components) for heterotetramers with different stoichiometries of ILT mutations

Shakera Eaf fast Eaf slow Eaf weighted Eab fast Eab slow Eab weighted 
 kCal/mol kCal/mol kCal/mol kCal/mol kCal/mol kCal/mol 
 − − −5.4 − − 24.8 
1ILT/3neu 17.5 18.1 25.8 20.1 0.6 12.9 
1ILT/3wt 29.3 23.6 35.3 14.3 15.1 18.5 
2ILT/2wt 23.2 16.5 20.4 10.5 13.3 16.9 
3ILT/1wt 21.8 19.6 25.8 8.5 15.9 14.3 
4ILT 25.8 19.5 25.6 11.3 4.4 16.9 
Shakera Eaf fast Eaf slow Eaf weighted Eab fast Eab slow Eab weighted 
 kCal/mol kCal/mol kCal/mol kCal/mol kCal/mol kCal/mol 
 − − −5.4 − − 24.8 
1ILT/3neu 17.5 18.1 25.8 20.1 0.6 12.9 
1ILT/3wt 29.3 23.6 35.3 14.3 15.1 18.5 
2ILT/2wt 23.2 16.5 20.4 10.5 13.3 16.9 
3ILT/1wt 21.8 19.6 25.8 8.5 15.9 14.3 
4ILT 25.8 19.5 25.6 11.3 4.4 16.9 
a

Rodriguez and Bezanilla, 1996.

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