Activation fit parameters
| Genotype | Islow | Ifast | ||||
| τslow | Aslow | Fraction (%) | τfast | Afast | Fraction (%) | |
| ms | pA/pF | ms | pA/pF | |||
| WT | 90.7 ± 6.6 | 11.6 ± 1.1a | 79 ± 3b | 9.1 ± 1.7 | 2.9 ± 0.4 | 21 ± 3b |
| (15) | ||||||
| HET | 77.9 ± 7.7 | 6.5 ± 1.2 | 69 ± 4 | 10.1 ± 1.9 | 2.5 ± 0.3 | 31 ± 4 |
| (12) | ||||||
| HOM | 79.4 ± 8.9 | 5.9 ± 0.6 | 61± 4 | 7.7 ± 0.9 | 3.7 ± 0.4 | 39 ± 4 |
| (14) | ||||||
| Genotype | Islow | Ifast | ||||
| τslow | Aslow | Fraction (%) | τfast | Afast | Fraction (%) | |
| ms | pA/pF | ms | pA/pF | |||
| WT | 90.7 ± 6.6 | 11.6 ± 1.1a | 79 ± 3b | 9.1 ± 1.7 | 2.9 ± 0.4 | 21 ± 3b |
| (15) | ||||||
| HET | 77.9 ± 7.7 | 6.5 ± 1.2 | 69 ± 4 | 10.1 ± 1.9 | 2.5 ± 0.3 | 31 ± 4 |
| (12) | ||||||
| HOM | 79.4 ± 8.9 | 5.9 ± 0.6 | 61± 4 | 7.7 ± 0.9 | 3.7 ± 0.4 | 39 ± 4 |
| (14) | ||||||
The activation phases of L-type currents evoked by test depolarizations from -50 mV to + 40 mV were fitted using Eq. 4 (see Materials and methods). Data are given as mean ± SEM, with the numbers in parentheses indicating the number of myotubes tested. The analysis of activation kinetics excluded cells in which tail current decay was obviously not monoexponential.
Significant differences among the three genotypes (P < 0.001, ANOVA).
P < 0.005, ANOVA.