Demographics and clinical characteristics of patients 1–4 with IPF
| Characteristic | Patient 1 | Patient 2 | Patient 3 | Patient 4 |
|---|---|---|---|---|
| Sex | M | M | M | M |
| Age at diagnosis (yr) | 32 | 57 | 72 | 52 |
| FVC (% predicted) | 89 | 78 | 102 | 62 |
| DLCOc (% predicted) | 40 | 65 | 75 | 47 |
| Smoking behavior | Former | Former | Former | Never |
| Pack years | 7 | 27 | 30 | NA |
| HRCT pattern | Probable UIP | Probable UIP | Probable UIP | Probable UIP |
| Inspiratory crackles | Yes | Yes | No | Yes |
| Digital clubbing | No | Yes | No | No |
| Additional STS | Liver disease | Peritoneal fibrosis | Liver disease; thrombocytopenia, RBC macrocytosis | No |
| T/Sobs-exp | −0.488 | −0.301 | −0.236 | −0.204 |
| T/S <10th percentile | Yes | Yes | Yes | Yes |
| Characteristic | Patient 1 | Patient 2 | Patient 3 | Patient 4 |
|---|---|---|---|---|
| Sex | M | M | M | M |
| Age at diagnosis (yr) | 32 | 57 | 72 | 52 |
| FVC (% predicted) | 89 | 78 | 102 | 62 |
| DLCOc (% predicted) | 40 | 65 | 75 | 47 |
| Smoking behavior | Former | Former | Former | Never |
| Pack years | 7 | 27 | 30 | NA |
| HRCT pattern | Probable UIP | Probable UIP | Probable UIP | Probable UIP |
| Inspiratory crackles | Yes | Yes | No | Yes |
| Digital clubbing | No | Yes | No | No |
| Additional STS | Liver disease | Peritoneal fibrosis | Liver disease; thrombocytopenia, RBC macrocytosis | No |
| T/Sobs-exp | −0.488 | −0.301 | −0.236 | −0.204 |
| T/S <10th percentile | Yes | Yes | Yes | Yes |
DLCOc, diffusing capacity of the lungs for carbon monoxide corrected for hemoglobin concentration; FVC, forced vital capacity; STS, short telomere syndrome; T/Sobs-exp, telomere length adjusted for age calculated by the difference between observed T/S ratio and the age-adjusted normal value.
As a benefit of your subscription, you can share temporary access to restricted articles.
Each link will stop working after 30 days or 10 uses. You may create up to 10 links in a 30 day period.
Please sign in to your personal account to gift article access.
As a benefit of your subscription, you can share temporary access to restricted articles.
Each link will stop working after 30 days or 10 uses. You may create up to 10 links in a 30 day period.
Gift articles remaining: --
Each link will stop working after 30 days or 10 uses. You may create up to 10 links in a 30 day period.
Gift articles remaining: --
As a benefit of your subscription, you can share temporary access to restricted articles.
Each link will stop working after 30 days or 10 uses.
You have reached the limit of 10 links within a 30 day period.
Sharing content requires targeting cookies to be enabled. Please update your cookie preferences to use this feature.