Patient immunological phenotypes from the analysis of whole blood samples
| Phenotype . | P1 . | Normal range . | P2 . | Normal range . |
|---|---|---|---|---|
| Lymphocytes/μl | 1,864 | 2,100 | ||
| T cells | ||||
| CD3+ | ||||
| % | 77 | 56–84 | 66 | 56–75 |
| /μl | 1,435 | 1,000–2,200 | 1,386 | 1,400–3,700 |
| CD4+ | ||||
| % | 26 | 31–52 | 32 | 28–47 |
| /mm3 | 485 | 530–1,300 | 672 | 700–2,200 |
| CD8+ | ||||
| % | 39 | 18–35 | 29 | 16–30 |
| /mm3 | 727 | 330–920 | 609 | 490–1,300 |
| CD45RA+/CD45+ (%) | 72 | 58–70 | 79 | 73–86 |
| CD31+CD45RA+/CD4+ (%) | 53 | 43–55 | 41 | 57–65 |
| CCR7+CD45RA+/CD8+ (%) | 65 | 52–68 | ND | |
| CCR7+CD45RA−/CD8+ (%) | 2 | 3–4 | ND | |
| CCR7−CD45RA−/CD8+ (%) | 12 | 11–20 | ND | |
| CCR7−CD45RA+/CD8+ (%) | 21 | 16–28 | ND | |
| B cells | ||||
| CD19+ | ||||
| % | 17 | 3.5–24 | 12 | 14–33 |
| /μl | 317 | 193–628 | 252 | 390–1,400 |
| CD27+/CD19+ (%) | 5 | 7–29 | ND | |
| CD27−IgD+/CD19+ (%) | 90 | 61.6–87.4 | ND | |
| CD27+IgD+/CD19+ (%) | 2 | 2.6–13.4 | ND | |
| CD27+IgD−/CD19+ (%) | 3 | 4–21.2 | ND | |
| CD24++CD38++CD27−IgD+/CD19+ (%) | 4 | 3.9–7.8 | ND | |
| CD24−CD38++/CD19+ (%) | 1 | 0.3–1.7 | ND | |
| CD21lowCD38low/CD19+ (%) | 2 | 0.9–3.3 | ND | |
| NK cells | ||||
| CD16+CD56+ | ||||
| % | 6 | 3–22 | 16 | |
| /μl | 112 | 70–480 | 336 |
| Phenotype . | P1 . | Normal range . | P2 . | Normal range . |
|---|---|---|---|---|
| Lymphocytes/μl | 1,864 | 2,100 | ||
| T cells | ||||
| CD3+ | ||||
| % | 77 | 56–84 | 66 | 56–75 |
| /μl | 1,435 | 1,000–2,200 | 1,386 | 1,400–3,700 |
| CD4+ | ||||
| % | 26 | 31–52 | 32 | 28–47 |
| /mm3 | 485 | 530–1,300 | 672 | 700–2,200 |
| CD8+ | ||||
| % | 39 | 18–35 | 29 | 16–30 |
| /mm3 | 727 | 330–920 | 609 | 490–1,300 |
| CD45RA+/CD45+ (%) | 72 | 58–70 | 79 | 73–86 |
| CD31+CD45RA+/CD4+ (%) | 53 | 43–55 | 41 | 57–65 |
| CCR7+CD45RA+/CD8+ (%) | 65 | 52–68 | ND | |
| CCR7+CD45RA−/CD8+ (%) | 2 | 3–4 | ND | |
| CCR7−CD45RA−/CD8+ (%) | 12 | 11–20 | ND | |
| CCR7−CD45RA+/CD8+ (%) | 21 | 16–28 | ND | |
| B cells | ||||
| CD19+ | ||||
| % | 17 | 3.5–24 | 12 | 14–33 |
| /μl | 317 | 193–628 | 252 | 390–1,400 |
| CD27+/CD19+ (%) | 5 | 7–29 | ND | |
| CD27−IgD+/CD19+ (%) | 90 | 61.6–87.4 | ND | |
| CD27+IgD+/CD19+ (%) | 2 | 2.6–13.4 | ND | |
| CD27+IgD−/CD19+ (%) | 3 | 4–21.2 | ND | |
| CD24++CD38++CD27−IgD+/CD19+ (%) | 4 | 3.9–7.8 | ND | |
| CD24−CD38++/CD19+ (%) | 1 | 0.3–1.7 | ND | |
| CD21lowCD38low/CD19+ (%) | 2 | 0.9–3.3 | ND | |
| NK cells | ||||
| CD16+CD56+ | ||||
| % | 6 | 3–22 | 16 | |
| /μl | 112 | 70–480 | 336 |
ND, not done.