Table 1.
Protein profiling in circulating lymphocytes
Protein nameaCD nameFCbAdjusted P valuec
Baseline PD vs. SD/PR 
CTLA-4 CD152 1.8 0.388 
NCAM CD56 1.66 0.388 
CD45RO CD45RO 1.52 0.388 
d43 PD vs. SD/PR 
CTLA-4 CD152 1.39 0.786 
PD-1 CD279 1.59 0.743 
CD45RO CD45RO 1.69 0.450 
BTLA CD272 −1.75 0.450 
CD19 CD19 −1.8 0.743 
HLA-DRA HLA-DRA −1.84 0.450 
CD40 CD40 −2.04 0.450 

NanoString protein profiling was used to test elutriated circulating lymphocytes. n = 16 (at baseline: 1 PR, 6 SD, 9 PD), and n = 11 (at d43: 1 PR, 4 SD, 6 PD). Immune checkpoint molecules are in bold.

a

Common protein name is listed. CD, cluster of differentiation name. FC, fold change.

b

Fold change is shown, where positive expression is higher in PD (Bad) compared to SD/PR (good) patient group. Negative correlations are shaded.

c

False discovery rate adjusted P value was calculated using Benjamini Hochberg correction.

[ViewLarge]
This Feature Is Available To Subscribers Only

or Create an Account

Close Modal
Close Modal