Table 1.
Summary of targeting neurons, microglia, oligodendrocytes, and astrocytes using rAAVs in BSCs
BSC cell type
.
Promoter
.
Capsid
.
Non-specific
hCBA
2/1, 2/2, 2/6, 2/8, 2/9
Microglia
CD68
2/6 with three mutations, Y731F/Y705F/T492V (TM6)
Neurons
CamKII, MAP-2
2/6, 2/8
Oligodendrocytes
MBP
2/8
Astrocytes
GFAP
2/8
BSC cell type
.
Promoter
.
Capsid
.
Non-specific
hCBA
2/1, 2/2, 2/6, 2/8, 2/9
Microglia
CD68
2/6 with three mutations, Y731F/Y705F/T492V (TM6)
Neurons
CamKII, MAP-2
2/6, 2/8
Oligodendrocytes
MBP
2/8
Astrocytes
GFAP
2/8
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