Table 1. Overview of TEIPP neoantigen... | Rockefeller University Press

Table 1.

Overview of TEIPP neoantigen candidates

#	Gene name	Peptide sequence^{^a}	Accession number^{^b}	HLA-A2 affinity (IC50)^{^c}	Expression^{^d}			T cell repertoire
#	Gene name	Peptide sequence^{^a}	Accession number^{^b}	HLA-A2 affinity (IC50)^{^c}	Tissue^{^e}	Normal	Cancer	T cell repertoire
Ubiquitous TEIPP
p1	ERGIC3	FLSELQYYL	Q9Y282	2	All	++	++	4/7
p4	TTYH3	ALFSFVTAL	Q9C0H2	10	All	+	+	1/3
p9	IGJ	VLAVFIKAV	P01591	52	All	++	++	1/3
p14	LRPAP1	FLGPWPAAS	D6REW6	353	All	++	++	14/14
p29	ARSA	LLALAAGLAV	P15289	79	All	++	++	9/10
p44	EMILIN2	FLYPFLSHL	Q9BXX0	4	All	+	++	4/7
p49	H2AFV	ILEYLTAEV	E5RJU1	30	All	++	++	6/9
p67	SEP15	LSEKLERI	O60613	15	All	+	+	4/8
Tissue-specific TEIPP
p2	IL12A	VLLDHLSLA	P29459	7	Mixed	+	+	3/7
p17	HPR	LLWGRQLFA	P00739	24	Liver	+++	+	6/7
p18	FSTL4	TLLGASLPA	Q6MZW2	27	Mixed	+	+++	5/7
p30	IFI30	LLLDVPTAAV	M0QZG3	10	Mixed	++	++	5/8
p32	CD79B	LLLSAEPVPA	P40259	41	Lymphoid	+	++	3/7
p34	PCDHGA6	LTLLGTLWGA	Q9Y5G7	24	Mixed	+/−	+/−	8/8
p35	C20orf141	SVLWLGALGL	Q9NUB4	161	Testis	+	+	16/16
p55	APCS	VIIKPLVWV	P02743	113	Liver	+++	+++	9/10

#	Gene name	Peptide sequence^{^a}	Accession number^{^b}	HLA-A2 affinity (IC50)^{^c}	Expression^{^d}			T cell repertoire
#	Gene name	Peptide sequence^{^a}	Accession number^{^b}	HLA-A2 affinity (IC50)^{^c}	Tissue^{^e}	Normal	Cancer	T cell repertoire
Ubiquitous TEIPP
p1	ERGIC3	FLSELQYYL	Q9Y282	2	All	++	++	4/7
p4	TTYH3	ALFSFVTAL	Q9C0H2	10	All	+	+	1/3
p9	IGJ	VLAVFIKAV	P01591	52	All	++	++	1/3
p14	LRPAP1	FLGPWPAAS	D6REW6	353	All	++	++	14/14
p29	ARSA	LLALAAGLAV	P15289	79	All	++	++	9/10
p44	EMILIN2	FLYPFLSHL	Q9BXX0	4	All	+	++	4/7
p49	H2AFV	ILEYLTAEV	E5RJU1	30	All	++	++	6/9
p67	SEP15	LSEKLERI	O60613	15	All	+	+	4/8
Tissue-specific TEIPP
p2	IL12A	VLLDHLSLA	P29459	7	Mixed	+	+	3/7
p17	HPR	LLWGRQLFA	P00739	24	Liver	+++	+	6/7
p18	FSTL4	TLLGASLPA	Q6MZW2	27	Mixed	+	+++	5/7
p30	IFI30	LLLDVPTAAV	M0QZG3	10	Mixed	++	++	5/8
p32	CD79B	LLLSAEPVPA	P40259	41	Lymphoid	+	++	3/7
p34	PCDHGA6	LTLLGTLWGA	Q9Y5G7	24	Mixed	+/−	+/−	8/8
p35	C20orf141	SVLWLGALGL	Q9NUB4	161	Testis	+	+	16/16
p55	APCS	VIIKPLVWV	P02743	113	Liver	+++	+++	9/10

Peptide sequences of the non-mutated neoantigens.

UniProt accession numbers.

Predicted peptide affinity binding in HLA-A2:01.

Protein expression scores are based on data from the Human Protein Atlas.

Protein expression based on the Cancer Genome Atlas database score.