Table 1.
Clinical characteristics of patients
Reference valuesaIV:1IV:2IV:3
Genotype  MT/MT MT/MT MT/MT 
Age (years)b  43 41 29 
Years of marriagec  20 17 11 
Height/weight (cm/kg)  182.9/70.0 167.6/70.0 167.6/50.0 
Semen parameters 
Semen volume (ml) >1.5 3.3 ± 0.9 2.0 ± 1.0 3.5 ± 0.7 
Semen pH Alkaline Alkaline Alkaline Alkaline 
Sperm concentration (106/ml) >15 18.0 ± 1.4 30.0 ± 0 17.3 ± 1.6 
Morphologically normal sperm (%) >4 76.8 ± 2.8 83.8 ± 0.3 78.4 ± 0.5 
Motile sperm (%) >40 11.5 ± 4.6 25.0 ± 10.6 15.1 ± 5.0 
Progressively motile sperm (%) >32 5.5 ± 1.8 17.5 ± 8.8 9.4 ± 3.1 
Reference valuesaIV:1IV:2IV:3
Genotype  MT/MT MT/MT MT/MT 
Age (years)b  43 41 29 
Years of marriagec  20 17 11 
Height/weight (cm/kg)  182.9/70.0 167.6/70.0 167.6/50.0 
Semen parameters 
Semen volume (ml) >1.5 3.3 ± 0.9 2.0 ± 1.0 3.5 ± 0.7 
Semen pH Alkaline Alkaline Alkaline Alkaline 
Sperm concentration (106/ml) >15 18.0 ± 1.4 30.0 ± 0 17.3 ± 1.6 
Morphologically normal sperm (%) >4 76.8 ± 2.8 83.8 ± 0.3 78.4 ± 0.5 
Motile sperm (%) >40 11.5 ± 4.6 25.0 ± 10.6 15.1 ± 5.0 
Progressively motile sperm (%) >32 5.5 ± 1.8 17.5 ± 8.8 9.4 ± 3.1 

Two independent experiments were performed. Data are presented as mean ± SEM. MT, the mutant allele.

a

Reference values were published in WHO (2010).

b

The current ages.

c

The current years of marriage.

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