| Bacterial strain . | Chronic inflammatory condition . |
|---|---|
| A. muciniphila | Ameliorates HFD-induced obesity and insulin resistance (Everard et al., 2013; Plovier et al., 2017) |
| Protects against atherosclerosis by decreasing gut permeability and preventing endotoxemia-induced inflammation (Li et al., 2016a) | |
| Improves efficacy of anti-cancer immunotherapy (Routy et al., 2018) | |
| B. fragilis | Restores the integrity of the intestinal barrier and ameliorates autistic-like behavior (Hsiao et al., 2013) |
| Suppresses neuro-inflammation in experimental model of MS (Wang et al., 2014a) | |
| B. adolescentis | Ameliorates HFD-induced colitis (Lim and Kim, 2017) |
| Bifidobacterium animalis spp. lactis | Restores the integrity of the intestinal barrier, thus reducing bacterial translocation and insulin sensitivity (Amar et al., 2011) |
| B. animalis spp. lactis and LGG | Improves HFD-induced obesity and insulin resistance (Alard et al., 2016) |
| B. longum | Reduces anxiety-like behavior in a mouse model of chemically induced colitis (Bercik et al., 2011) |
| Restores the integrity of colonic mucus layer impaired by HFD (Schroeder et al., 2018) | |
| Bifidobacterium pseudocatenulatum | Reduces weight gain, body fat, fasting glucose, and insulin resistance in mice with HFD-induced obesity (Zhao et al., 2018) |
| Christensenella minuta | Reduces weight gain in mice inoculated with obese human fecal samples (Goodrich et al., 2014) |
| C. scindens | Protects against antibiotic-induced C. difficile colitis (Buffie et al., 2015) |
| F. prausnitzii | Alleviates inflammation in chemically induced models of colitis (Sokol et al., 2008; Quévrain et al., 2016; Breyner et al., 2017) |
| L. johnsonii | Provides airway protection against allergen challenge and respiratory virus infection (Fujimura et al., 2014; Fonseca et al., 2017) |
| L. murinus | Protects from dextran sodium sulfate–induced colitis by promoting increase in T reg cells in the colon (Tang et al., 2015) |
| L. plantarum | Recovers growth stunting in juvenile GF mice associated with somatotropic axis signaling (Schwarzer et al., 2016) |
| Lowers fasting blood glucose and triglyceride levels (Toshimitsu et al., 2017) | |
| L. reuteri | Restores social behavior in offspring of dams fed HFD (Buffington et al., 2016) |
| Restores despair behavior induced by exposure to chronic stress via suppression of tryptophan/kynurenine metabolism (Marin et al., 2017) | |
| L. reuteri, L. murinus, and Lactobacillus taiwanensis | Attenuates intestinal inflammation in experimental model of colitis (Lamas et al., 2016) |
| LGG | Ameliorates ASD-like behavior by modulating the expression of GABA receptors in the brain (Bravo et al., 2011) |
| Lactobacillus sakei | Improves HFD-induced obesity and hyperglycemia by reducing inflammation and increasing the expression of colon tight junction proteins (Lim et al., 2016) |
| Bacterial strain . | Chronic inflammatory condition . |
|---|---|
| A. muciniphila | Ameliorates HFD-induced obesity and insulin resistance (Everard et al., 2013; Plovier et al., 2017) |
| Protects against atherosclerosis by decreasing gut permeability and preventing endotoxemia-induced inflammation (Li et al., 2016a) | |
| Improves efficacy of anti-cancer immunotherapy (Routy et al., 2018) | |
| B. fragilis | Restores the integrity of the intestinal barrier and ameliorates autistic-like behavior (Hsiao et al., 2013) |
| Suppresses neuro-inflammation in experimental model of MS (Wang et al., 2014a) | |
| B. adolescentis | Ameliorates HFD-induced colitis (Lim and Kim, 2017) |
| Bifidobacterium animalis spp. lactis | Restores the integrity of the intestinal barrier, thus reducing bacterial translocation and insulin sensitivity (Amar et al., 2011) |
| B. animalis spp. lactis and LGG | Improves HFD-induced obesity and insulin resistance (Alard et al., 2016) |
| B. longum | Reduces anxiety-like behavior in a mouse model of chemically induced colitis (Bercik et al., 2011) |
| Restores the integrity of colonic mucus layer impaired by HFD (Schroeder et al., 2018) | |
| Bifidobacterium pseudocatenulatum | Reduces weight gain, body fat, fasting glucose, and insulin resistance in mice with HFD-induced obesity (Zhao et al., 2018) |
| Christensenella minuta | Reduces weight gain in mice inoculated with obese human fecal samples (Goodrich et al., 2014) |
| C. scindens | Protects against antibiotic-induced C. difficile colitis (Buffie et al., 2015) |
| F. prausnitzii | Alleviates inflammation in chemically induced models of colitis (Sokol et al., 2008; Quévrain et al., 2016; Breyner et al., 2017) |
| L. johnsonii | Provides airway protection against allergen challenge and respiratory virus infection (Fujimura et al., 2014; Fonseca et al., 2017) |
| L. murinus | Protects from dextran sodium sulfate–induced colitis by promoting increase in T reg cells in the colon (Tang et al., 2015) |
| L. plantarum | Recovers growth stunting in juvenile GF mice associated with somatotropic axis signaling (Schwarzer et al., 2016) |
| Lowers fasting blood glucose and triglyceride levels (Toshimitsu et al., 2017) | |
| L. reuteri | Restores social behavior in offspring of dams fed HFD (Buffington et al., 2016) |
| Restores despair behavior induced by exposure to chronic stress via suppression of tryptophan/kynurenine metabolism (Marin et al., 2017) | |
| L. reuteri, L. murinus, and Lactobacillus taiwanensis | Attenuates intestinal inflammation in experimental model of colitis (Lamas et al., 2016) |
| LGG | Ameliorates ASD-like behavior by modulating the expression of GABA receptors in the brain (Bravo et al., 2011) |
| Lactobacillus sakei | Improves HFD-induced obesity and hyperglycemia by reducing inflammation and increasing the expression of colon tight junction proteins (Lim et al., 2016) |