| Gene (protein) . | Labeled cells (CNS) . | Genetic lines . | Antibodies . | Notes . | Reference . |
|---|---|---|---|---|---|
| Gfap (GFAP) | Astrocytes + NPCs | Fluorescent reporter, Cre, CreERT2 | Y | Upregulated in some reactive astrocytes | Brenner et al., 1994; Zhuo et al., 2001; Su et al., 2004; Ganat et al., 2006; Liu et al., 2010 |
| Aldh1l1 (ALDH1L1) | Astrocytes | Fluorescent reporter, CreERT2 (new) | Y | Cahoy et al., 2008; Srinivasan et al., 2016; Winchenbach et al., 2016 | |
| Slc1a3 (GLAST) | Astrocytes + NPCs | Fluorescent reporter, CreERT | Y | Developed by Jeremy Nathans (Mouse Genome Informatics) | Regan et al., 2007; Kang et al., 2010; de Melo et al., 2012; Wang et al., 2012 |
| Slc1a2 (GLT1) | Astrocytes + NPCs | Fluorescent reporter | Y | Regan et al., 2007; Yang et al., 2011 | |
| S100b (S100B) | Astrocytes + OL lineage | Fluorescent reporter, CreERT2 | Y | Zuo et al., 2004; McMahon et al., 2008; Harding et al., 2011 | |
| Gjb6 (CX30) | Astrocytes + NPCs | CreERT2 | Y | Slezak et al., 2007; Srinivasan et al., 2016 | |
| Slc6a11 (GAT3) | Astrocytes + NPCs | CreERT2 | Y | Srinivasan et al., 2016 | |
| Nes (NESTIN) | Astrocytes + NPCs | Fluorescent reporter, Cre, CreERT2 | Y | Upregulated in some reactive astrocytes | Betz et al., 1996; Tronche et al., 1999; Battiste et al., 2007; Lagace et al., 2007 |
| Vim (VIMENTIN) | Astrocytes + NPCs | Fluorescent reporter, LacZ | Y | Upregulated in some reactive astrocytes | Colucci-Guyon et al., 1994 |
| C3 | Astrocyte + certain Cx3cr1+ cells | Fluorescent reporter (not finalized) | Y (human) | Upregulated in A1 reactive astrocytes; in situ hybridization required for murine tissue | Liddelow et al., 2017 |
| Gene (protein) . | Labeled cells (CNS) . | Genetic lines . | Antibodies . | Notes . | Reference . |
|---|---|---|---|---|---|
| Gfap (GFAP) | Astrocytes + NPCs | Fluorescent reporter, Cre, CreERT2 | Y | Upregulated in some reactive astrocytes | Brenner et al., 1994; Zhuo et al., 2001; Su et al., 2004; Ganat et al., 2006; Liu et al., 2010 |
| Aldh1l1 (ALDH1L1) | Astrocytes | Fluorescent reporter, CreERT2 (new) | Y | Cahoy et al., 2008; Srinivasan et al., 2016; Winchenbach et al., 2016 | |
| Slc1a3 (GLAST) | Astrocytes + NPCs | Fluorescent reporter, CreERT | Y | Developed by Jeremy Nathans (Mouse Genome Informatics) | Regan et al., 2007; Kang et al., 2010; de Melo et al., 2012; Wang et al., 2012 |
| Slc1a2 (GLT1) | Astrocytes + NPCs | Fluorescent reporter | Y | Regan et al., 2007; Yang et al., 2011 | |
| S100b (S100B) | Astrocytes + OL lineage | Fluorescent reporter, CreERT2 | Y | Zuo et al., 2004; McMahon et al., 2008; Harding et al., 2011 | |
| Gjb6 (CX30) | Astrocytes + NPCs | CreERT2 | Y | Slezak et al., 2007; Srinivasan et al., 2016 | |
| Slc6a11 (GAT3) | Astrocytes + NPCs | CreERT2 | Y | Srinivasan et al., 2016 | |
| Nes (NESTIN) | Astrocytes + NPCs | Fluorescent reporter, Cre, CreERT2 | Y | Upregulated in some reactive astrocytes | Betz et al., 1996; Tronche et al., 1999; Battiste et al., 2007; Lagace et al., 2007 |
| Vim (VIMENTIN) | Astrocytes + NPCs | Fluorescent reporter, LacZ | Y | Upregulated in some reactive astrocytes | Colucci-Guyon et al., 1994 |
| C3 | Astrocyte + certain Cx3cr1+ cells | Fluorescent reporter (not finalized) | Y (human) | Upregulated in A1 reactive astrocytes; in situ hybridization required for murine tissue | Liddelow et al., 2017 |
OL, oligodendrocyte; Y, yes.