| Characteristic . | Total . | Euthyroid . | Mild SH . | Severe SH . | P value . |
|---|---|---|---|---|---|
| Serum TSH (mIU/liter) | 0.27 ≤ TSH < 4.2 | 4.2 ≤ TSH < 10 | 10 ≤ TSH | ||
| Age (yr) | 54.32 (7.65) | 53.59 (7.28) | 55.81 (8.24)a | 58.84 (8.14)a,b | <0.001 |
| Male sex | 291 (26.3) | 244 (31.0) | 42 (15.1) | 5 (13.5) | <0.001 |
| Smoking | 482 (43.7) | 338 (42.9) | 126 (45.2) | 18 (48.6) | 0.673 |
| Drinking | 305 (27.6) | 230 (29.2) | 28 (24.4) | 7 (18.9) | 0.079 |
| BMI (kg/m2) | 25.22 (3.53) | 25.13 (3.56) | 25.34 (3.46) | 26.15 (3.24) | 0.276 |
| SBP (mm Hg) | 134.04 (18.79) | 131.63 (18.36) | 139.84 (18.71)a | 142.08 (18.18)a | <0.001 |
| DBP (mm Hg) | 79.92 (11.49) | 79.40 (11.92) | 81.39 (10.10)a | 80.16 (11.74) | 0.075 |
| FT3 (pmol/ml) | 4.91 (0.64) | 4.93 (0.66) | 4.90 (0.60) | 4.83 (0.55) | 0.702 |
| FT4 (pmol/ml) | 15.69 (2.17) | 16.24 (2.05) | 14.45 (1.85)a | 13.50 (1.57)a,b | <0.001 |
| TSH (mIU/liter) | 2.96 (2.58) | 2.32 (1.49) | 5.45 (2.12) | 11.63 (2.72) | N/A |
| TC (mmol/liter) | 5.19 (1.19) | 5.01 (1.15) | 5.63 (1.16)a | 5.86 (1.28)a | <0.001 |
| TG (mmol/liter) | 1.10 (0.75) | 1.04 (0.73) | 1.22 (0.82) | 1.32 (0.73) | 0.363 |
| LDL-C (mmol/liter) | 3.00 (0.86) | 2.91 (0.84) | 3.20 (0.83)a | 3.47 (0.95)a,b | <0.001 |
| HDL-C (mmol/liter) | 1.42 (0.33) | 1.41 (0.33) | 1.46 (0.35)a | 1.40 (0.30) | 0.141 |
| FPG (mmol/liter) | 5.78 (0.99) | 5.78 (1.01) | 5.79 (0.94) | 5.57 (0.84) | 0.537 |
| Characteristic . | Total . | Euthyroid . | Mild SH . | Severe SH . | P value . |
|---|---|---|---|---|---|
| Serum TSH (mIU/liter) | 0.27 ≤ TSH < 4.2 | 4.2 ≤ TSH < 10 | 10 ≤ TSH | ||
| Age (yr) | 54.32 (7.65) | 53.59 (7.28) | 55.81 (8.24)a | 58.84 (8.14)a,b | <0.001 |
| Male sex | 291 (26.3) | 244 (31.0) | 42 (15.1) | 5 (13.5) | <0.001 |
| Smoking | 482 (43.7) | 338 (42.9) | 126 (45.2) | 18 (48.6) | 0.673 |
| Drinking | 305 (27.6) | 230 (29.2) | 28 (24.4) | 7 (18.9) | 0.079 |
| BMI (kg/m2) | 25.22 (3.53) | 25.13 (3.56) | 25.34 (3.46) | 26.15 (3.24) | 0.276 |
| SBP (mm Hg) | 134.04 (18.79) | 131.63 (18.36) | 139.84 (18.71)a | 142.08 (18.18)a | <0.001 |
| DBP (mm Hg) | 79.92 (11.49) | 79.40 (11.92) | 81.39 (10.10)a | 80.16 (11.74) | 0.075 |
| FT3 (pmol/ml) | 4.91 (0.64) | 4.93 (0.66) | 4.90 (0.60) | 4.83 (0.55) | 0.702 |
| FT4 (pmol/ml) | 15.69 (2.17) | 16.24 (2.05) | 14.45 (1.85)a | 13.50 (1.57)a,b | <0.001 |
| TSH (mIU/liter) | 2.96 (2.58) | 2.32 (1.49) | 5.45 (2.12) | 11.63 (2.72) | N/A |
| TC (mmol/liter) | 5.19 (1.19) | 5.01 (1.15) | 5.63 (1.16)a | 5.86 (1.28)a | <0.001 |
| TG (mmol/liter) | 1.10 (0.75) | 1.04 (0.73) | 1.22 (0.82) | 1.32 (0.73) | 0.363 |
| LDL-C (mmol/liter) | 3.00 (0.86) | 2.91 (0.84) | 3.20 (0.83)a | 3.47 (0.95)a,b | <0.001 |
| HDL-C (mmol/liter) | 1.42 (0.33) | 1.41 (0.33) | 1.46 (0.35)a | 1.40 (0.30) | 0.141 |
| FPG (mmol/liter) | 5.78 (0.99) | 5.78 (1.01) | 5.79 (0.94) | 5.57 (0.84) | 0.537 |
Intergroup comparisons were done with post-hoc Hochberg’s GT2 test. Data are expressed as the mean (SD) or median (interquantile range) depending on the type of variance. TG was log-transformed before being analyzed by one-way ANOVA. Bold text indicates that P values are statistically significant. BMI, body mass index; DBP, diastolic blood pressure; SBP, systolic blood pressure.
P < 0.05 vs. euthyroid control.
P < 0.05 vs. mild SH.