| Patient . | Case . | Sex . | Age (yr) . | Age onset (yr)/SCC . | HPV type . | Skin lesions (location) . | SCC . | Reference . |
|---|---|---|---|---|---|---|---|---|
| P1 | A1.viii.4 | F | 50 | 12/no | Unknown | Head and hands | No | Rueda (1993) |
| P2 | A1.viii.7 | M | 47* | 6/18 | 8, 17, 20 | Head, neck, trunk, hands, legs, and feet | Forehead | Rueda (1993), case 11 |
| P3 | A1.viii.10 | F | 46 | 7/13 | 8, 20 | Head, trunk, legs, arms, and hands | Forehead, lips | Rueda (1993), case 12 |
| P4 | A1.viii.12 | F | 44 | 7/no | 8 | Head and trunk | No | Rueda (1993) |
| P5 | A1.viii.15 | M | 37 | 5/17 | 8, 20 | Head, trunk, hands, and upper legs | Forehead | Rueda (1993), case 13 |
| P6 | A1.vi.13 | M | 47* | 1/15 | Unknown | Head, trunk, hands, and legs | Nose, trunk | Rueda (1993), case 6 |
| P7 | A1.viii.30 | M | 47 | 5/10 | 5, 17, 36 | Head, trunk, arms, hands, and legs | Canthus, nose | Rueda (1993), case 7 |
| P8 | A2.ii.1 | F | 78* | 1/47 | 5, 8, 20, 24 | Head, trunk, and extremities | Forehead | Rueda (1993) and Rueda and Rodriguez (1976), case 1 both papers |
| P9 | A2.ii.10 | F | Unknown | 5/38 | 8, 9 | Head, trunk, and extremities | - | Rueda (1993) and Rueda and Rodriguez (1976), case 2 both papers |
| P10 | A2.ii.12 | M | 48* | 1/26 | Unknown | Head, trunk, and extremities | Forehead, lips | Rueda (1993) and Rueda and Rodriguez (1976), case 3 both papers |
| P11 | A2.ii.13 | M | 47* | 3/27 | 5, 8, 20 | Head, trunk, and extremities | Forehead | Rueda (1993) and Rueda and Rodriguez (1976), case 4 both papers |
| P12 | B.ii.2 | M | 72* | 23/43 | 8, 15 | Head, trunk, arms, hands, and legs | Forehead, check, ear | Kienzler et al. (1979) |
| P13 | C.ii.1 | F | 71* | Childhood/35 | 5 | Head, neck, hands, and legs | Scalp, nose | Lutz (1946) and Arnold et al. (2011), case 1 both papers |
| P14 | C.ii.2 | F | 91* | <7/52 | 5 | Head, neck, and hands | Nose, hand, neck, forehead, scalp | Lutz (1946) and Arnold et al. (2011), case 2 both papers |
| P15 | D.iv.2 | F | 59 | Childhood/54 | 5 | Head, neck, arms, hand, knee, and lower leg | Forehead, nose | Imahorn et al. (2017) |
| P16 | E.iv.4 | F | 21* | 7/unknown | Unknown | Face and trunk | Multiple (sun-exposed skin) | Saka et al. (2009) |
| P17 | E.iv.6 | F | Unknown* | 5/unknown | Unknown | Face and trunk | Unknown | Saka et al. (2009) |
| P18 | E.iv.8 | F | Unknown* | Unknown/unknown | Unknown | Unknown | Unknown | Saka et al. (2009) |
| P19 | E.iv.10 | M | 14 | 2/unknown | Unknown | Face and trunk | Unknown | Saka et al. (2009) |
| P20 | F.v.2 | M | 47 | 3/46 | Unknown | Head, neck, trunk, and upper and lower limb | Forehead (basosquamous carcinoma) | This study |
| P21 | F.v.3 | M | 44 | 2/no | Unknown | Head, neck, trunk, and upper and lower limb | - | This study |
| P22 | F.v.7 | F | 30 | 5/no | Unknown | Head, neck, trunk, and upper and lower limb | - | This study |
| P23 | F.vi.1 | F | 22 | 1/no | Unknown | Head, neck, trunk, and upper and lower limb | - | This study |
| P24 | F.vi.2 | M | 21 | 4/no | Unknown | Head, neck, trunk, and upper and lower limb | - | This study |
| Patient . | Case . | Sex . | Age (yr) . | Age onset (yr)/SCC . | HPV type . | Skin lesions (location) . | SCC . | Reference . |
|---|---|---|---|---|---|---|---|---|
| P1 | A1.viii.4 | F | 50 | 12/no | Unknown | Head and hands | No | Rueda (1993) |
| P2 | A1.viii.7 | M | 47* | 6/18 | 8, 17, 20 | Head, neck, trunk, hands, legs, and feet | Forehead | Rueda (1993), case 11 |
| P3 | A1.viii.10 | F | 46 | 7/13 | 8, 20 | Head, trunk, legs, arms, and hands | Forehead, lips | Rueda (1993), case 12 |
| P4 | A1.viii.12 | F | 44 | 7/no | 8 | Head and trunk | No | Rueda (1993) |
| P5 | A1.viii.15 | M | 37 | 5/17 | 8, 20 | Head, trunk, hands, and upper legs | Forehead | Rueda (1993), case 13 |
| P6 | A1.vi.13 | M | 47* | 1/15 | Unknown | Head, trunk, hands, and legs | Nose, trunk | Rueda (1993), case 6 |
| P7 | A1.viii.30 | M | 47 | 5/10 | 5, 17, 36 | Head, trunk, arms, hands, and legs | Canthus, nose | Rueda (1993), case 7 |
| P8 | A2.ii.1 | F | 78* | 1/47 | 5, 8, 20, 24 | Head, trunk, and extremities | Forehead | Rueda (1993) and Rueda and Rodriguez (1976), case 1 both papers |
| P9 | A2.ii.10 | F | Unknown | 5/38 | 8, 9 | Head, trunk, and extremities | - | Rueda (1993) and Rueda and Rodriguez (1976), case 2 both papers |
| P10 | A2.ii.12 | M | 48* | 1/26 | Unknown | Head, trunk, and extremities | Forehead, lips | Rueda (1993) and Rueda and Rodriguez (1976), case 3 both papers |
| P11 | A2.ii.13 | M | 47* | 3/27 | 5, 8, 20 | Head, trunk, and extremities | Forehead | Rueda (1993) and Rueda and Rodriguez (1976), case 4 both papers |
| P12 | B.ii.2 | M | 72* | 23/43 | 8, 15 | Head, trunk, arms, hands, and legs | Forehead, check, ear | Kienzler et al. (1979) |
| P13 | C.ii.1 | F | 71* | Childhood/35 | 5 | Head, neck, hands, and legs | Scalp, nose | Lutz (1946) and Arnold et al. (2011), case 1 both papers |
| P14 | C.ii.2 | F | 91* | <7/52 | 5 | Head, neck, and hands | Nose, hand, neck, forehead, scalp | Lutz (1946) and Arnold et al. (2011), case 2 both papers |
| P15 | D.iv.2 | F | 59 | Childhood/54 | 5 | Head, neck, arms, hand, knee, and lower leg | Forehead, nose | Imahorn et al. (2017) |
| P16 | E.iv.4 | F | 21* | 7/unknown | Unknown | Face and trunk | Multiple (sun-exposed skin) | Saka et al. (2009) |
| P17 | E.iv.6 | F | Unknown* | 5/unknown | Unknown | Face and trunk | Unknown | Saka et al. (2009) |
| P18 | E.iv.8 | F | Unknown* | Unknown/unknown | Unknown | Unknown | Unknown | Saka et al. (2009) |
| P19 | E.iv.10 | M | 14 | 2/unknown | Unknown | Face and trunk | Unknown | Saka et al. (2009) |
| P20 | F.v.2 | M | 47 | 3/46 | Unknown | Head, neck, trunk, and upper and lower limb | Forehead (basosquamous carcinoma) | This study |
| P21 | F.v.3 | M | 44 | 2/no | Unknown | Head, neck, trunk, and upper and lower limb | - | This study |
| P22 | F.v.7 | F | 30 | 5/no | Unknown | Head, neck, trunk, and upper and lower limb | - | This study |
| P23 | F.vi.1 | F | 22 | 1/no | Unknown | Head, neck, trunk, and upper and lower limb | - | This study |
| P24 | F.vi.2 | M | 21 | 4/no | Unknown | Head, neck, trunk, and upper and lower limb | - | This study |
Information collected from listed references or oral communication with the treating physicians. Please see Fig. 1 A for individual deidentifiers. F, female; M, male; ages of death are marked with asterisks.