| Gene set name . | Systematic name . | NES . | P value . | Q value . |
|---|---|---|---|---|
| HALLMARK_P53_PATHWAY | M5939 | 2.00 | <0.01 | 0.019 |
| HALLMARK_INFLAMMATORY_RESPONSE | M5932 | 1.98 | <0.01 | 0.019 |
| HALLMARK_APOPTOSIS | M5902 | 1.90 | <0.01 | 0.027 |
| HALLMARK_HYPOXIA | M5891 | 1.86 | <0.01 | 0.025 |
| HALLMARK_IL2_STAT5_SIGNALING | M5947 | 1.83 | <0.01 | 0.028 |
| HALLMARK_KRAS_SIGNALING_UP | M5953 | 1.82 | <0.01 | 0.026 |
| HALLMARK_UV_RESPONSE_DN | M5942 | 1.80 | <0.01 | 0.025 |
| HALLMARK_INTERFERON_ALPHA_RESPONSE | M5911 | 1.78 | <0.01 | 0.025 |
| HALLMARK_INTERFERON_GAMMA_RESPONSE | M5913 | 1.76 | <0.01 | 0.024 |
| HALLMARK_NOTCH_SIGNALING | M5903 | 1.72 | <0.01 | 0.029 |
| HALLMARK_IL6_JAK_STAT3_SIGNALING | M5897 | 1.72 | <0.01 | 0.028 |
| HALLMARK_MYOGENESIS | M5909 | 1.58 | <0.01 | 0.044 |
| HALLMARK_HEME_METABOLISM | M5945 | 1.55 | <0.01 | 0.054 |
| HALLMARK_TNFA_SIGNALING_VIA_NFKB | M5890 | 1.54 | <0.01 | 0.053 |
| HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION | M5930 | 1.51 | <0.01 | 0.062 |
| HALLMARK_APICAL_SURFACE | M5916 | 1.40 | 0.042 | 0.098 |
| HALLMARK_ESTROGEN_RESPONSE_LATE | M5907 | 1.38 | 0.05 | 0.106 |
| Gene set name . | Systematic name . | NES . | P value . | Q value . |
|---|---|---|---|---|
| HALLMARK_P53_PATHWAY | M5939 | 2.00 | <0.01 | 0.019 |
| HALLMARK_INFLAMMATORY_RESPONSE | M5932 | 1.98 | <0.01 | 0.019 |
| HALLMARK_APOPTOSIS | M5902 | 1.90 | <0.01 | 0.027 |
| HALLMARK_HYPOXIA | M5891 | 1.86 | <0.01 | 0.025 |
| HALLMARK_IL2_STAT5_SIGNALING | M5947 | 1.83 | <0.01 | 0.028 |
| HALLMARK_KRAS_SIGNALING_UP | M5953 | 1.82 | <0.01 | 0.026 |
| HALLMARK_UV_RESPONSE_DN | M5942 | 1.80 | <0.01 | 0.025 |
| HALLMARK_INTERFERON_ALPHA_RESPONSE | M5911 | 1.78 | <0.01 | 0.025 |
| HALLMARK_INTERFERON_GAMMA_RESPONSE | M5913 | 1.76 | <0.01 | 0.024 |
| HALLMARK_NOTCH_SIGNALING | M5903 | 1.72 | <0.01 | 0.029 |
| HALLMARK_IL6_JAK_STAT3_SIGNALING | M5897 | 1.72 | <0.01 | 0.028 |
| HALLMARK_MYOGENESIS | M5909 | 1.58 | <0.01 | 0.044 |
| HALLMARK_HEME_METABOLISM | M5945 | 1.55 | <0.01 | 0.054 |
| HALLMARK_TNFA_SIGNALING_VIA_NFKB | M5890 | 1.54 | <0.01 | 0.053 |
| HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION | M5930 | 1.51 | <0.01 | 0.062 |
| HALLMARK_APICAL_SURFACE | M5916 | 1.40 | 0.042 | 0.098 |
| HALLMARK_ESTROGEN_RESPONSE_LATE | M5907 | 1.38 | 0.05 | 0.106 |
The transcriptome data of three-cell-divided HSCs cultured with or without Nifedipine were subjected to GSEA, and the threshold was set at P value < 0.05. The normalized enrichment score (NES) reflects the degree to which a gene set is overrepresented at the top or bottom of a ranked list of genes. Bold indicates the gene sets in which q < 0.05.