Table 2. Immune cell phenotyping in... | Rockefeller University Press

Table 2.

Immune cell phenotyping in CIN85 deficiency

	Pat. no.1	Reference values	Pat no. 1	Reference values
	%	%	cells/µl	cells/µl
Lymphocytes
CD4	40	30.4–52.9	1,245	608–1,217
CD8	26.2	14–40	815	300–1,300
NK cells	8.7	4–51
B cells	5.3	7.8–23.7	165	119–578
γδ of CD3 T cells	2.4	<10^{^a}
CD4 subpopulations
CD45RA	63	49.2–72	784	311–781
RTE of CD45RA	54.3	33.5–58.2
T reg	3.1	2.8–7.2	38	25–64
CD8 subpopulations
Naive	50.7	20–95	413	78–640
Terminally differentiated	3.7	9–65	30	35–420
Effector memory	9.4	4–100	77	16–810
Central memory	7.0	0.42–18	57	2–86
B cell subpopulations	5.3	7.8–23.7	165	119–578
Transitional B cells	5.9	1.5–7.3	10	2–41
Naive B cells	83.6	64.6–80.1	138	83–398
IgM/IgD memory	4.6	4.7–15.5	8	10–74
IgM only memory	0.1	1.6–11.3	1	3–39
IgG switched memory	2.5	2.1–9.4	4	7–32
IgA switched memory	1.1	1.2–3.8	2	4–13
Plasmablasts	0.3	0.5–4.1^{^a}
Kappa/lambda ratio	1.2	1.1–2.0^{^a}
CD21^low	1.7	1.1–6.9^{^a}

	Pat. no.1	Reference values	Pat no. 1	Reference values
	%	%	cells/µl	cells/µl
Lymphocytes
CD4	40	30.4–52.9	1,245	608–1,217
CD8	26.2	14–40	815	300–1,300
NK cells	8.7	4–51
B cells	5.3	7.8–23.7	165	119–578
γδ of CD3 T cells	2.4	<10^{^a}
CD4 subpopulations
CD45RA	63	49.2–72	784	311–781
RTE of CD45RA	54.3	33.5–58.2
T reg	3.1	2.8–7.2	38	25–64
CD8 subpopulations
Naive	50.7	20–95	413	78–640
Terminally differentiated	3.7	9–65	30	35–420
Effector memory	9.4	4–100	77	16–810
Central memory	7.0	0.42–18	57	2–86
B cell subpopulations	5.3	7.8–23.7	165	119–578
Transitional B cells	5.9	1.5–7.3	10	2–41
Naive B cells	83.6	64.6–80.1	138	83–398
IgM/IgD memory	4.6	4.7–15.5	8	10–74
IgM only memory	0.1	1.6–11.3	1	3–39
IgG switched memory	2.5	2.1–9.4	4	7–32
IgA switched memory	1.1	1.2–3.8	2	4–13
Plasmablasts	0.3	0.5–4.1^{^a}
Kappa/lambda ratio	1.2	1.1–2.0^{^a}
CD21^low	1.7	1.1–6.9^{^a}

Variations from reference values are indicated in bold. RTE, recent thymic emigrants. T reg, regulatory T cells.

Internal diagnostic reference values.