| Fold change . | P-value . | Gene symbol . |
|---|---|---|
| 2.0 | 0.0006 | Gdpd3 |
| 2.0 | 0.0191 | Xpr1 |
| 2.0 | 0.0064 | Mterfd2 |
| 2.0 | 0.0492 | Nrp2 |
| 1.6 | 0.0439 | Rnf121 |
| 1.6 | 0.0277 | Inpp4b |
| 1.6 | 0.0398 | Fusip1 |
| 1.6 | 0.0228 | Folr2 |
| 1.5 | 0.0325 | Aurka |
| 1.5 | 0.0336 | Pptc7 |
| 1.5 | 0.0461 | Lmna |
| 1.5 | 0.0364 | Birc5 |
| 1.5 | 0.0346 | Sept11 |
| 1.5 | 0.0188 | Nrp2 |
| 1.5 | 0.0362 | Baz2b |
| −1.5 | 0.0366 | Upf2 |
| −1.5 | 0.0345 | Chd1 |
| −1.5 | 0.0204 | Ppfia1 |
| −1.5 | 0.0102 | Wdr51b |
| −1.5 | 0.0142 | Arhgap22 |
| −1.5 | 0.0097 | Helb |
| −1.5 | 0.0146 | Cias1 |
| −1.5 | 0.0015 | Slc35c2 |
| −1.5 | 0.0386 | Mef2c |
| −1.6 | 0.0028 | Nlrp3 |
| −1.6 | 0.0473 | H3f3b |
| −1.6 | 0.0119 | Agl |
| −1.6 | 0.0004 | Abcd3 |
| −1.6 | 0.0030 | Slc35c2 |
| −1.7 | 0.0293 | Slc44a2 |
| −1.7 | 0.0348 | St3gal5 |
| −1.7 | 0.0027 | Anxa3 |
| −1.7 | 0.0083 | Olfml3 |
| −1.7 | 0.0033 | Tnfsf9 |
| Fold change . | P-value . | Gene symbol . |
|---|---|---|
| 2.0 | 0.0006 | Gdpd3 |
| 2.0 | 0.0191 | Xpr1 |
| 2.0 | 0.0064 | Mterfd2 |
| 2.0 | 0.0492 | Nrp2 |
| 1.6 | 0.0439 | Rnf121 |
| 1.6 | 0.0277 | Inpp4b |
| 1.6 | 0.0398 | Fusip1 |
| 1.6 | 0.0228 | Folr2 |
| 1.5 | 0.0325 | Aurka |
| 1.5 | 0.0336 | Pptc7 |
| 1.5 | 0.0461 | Lmna |
| 1.5 | 0.0364 | Birc5 |
| 1.5 | 0.0346 | Sept11 |
| 1.5 | 0.0188 | Nrp2 |
| 1.5 | 0.0362 | Baz2b |
| −1.5 | 0.0366 | Upf2 |
| −1.5 | 0.0345 | Chd1 |
| −1.5 | 0.0204 | Ppfia1 |
| −1.5 | 0.0102 | Wdr51b |
| −1.5 | 0.0142 | Arhgap22 |
| −1.5 | 0.0097 | Helb |
| −1.5 | 0.0146 | Cias1 |
| −1.5 | 0.0015 | Slc35c2 |
| −1.5 | 0.0386 | Mef2c |
| −1.6 | 0.0028 | Nlrp3 |
| −1.6 | 0.0473 | H3f3b |
| −1.6 | 0.0119 | Agl |
| −1.6 | 0.0004 | Abcd3 |
| −1.6 | 0.0030 | Slc35c2 |
| −1.7 | 0.0293 | Slc44a2 |
| −1.7 | 0.0348 | St3gal5 |
| −1.7 | 0.0027 | Anxa3 |
| −1.7 | 0.0083 | Olfml3 |
| −1.7 | 0.0033 | Tnfsf9 |
WT PyMT, S1PR1ΔMΦ PyMT, WT MCA, and S1PR1ΔMΦ MCA CD11bhi TAM (two replicates consisting of TAM from two to three individual animals for each group) were sorted by FACS and subjected to whole-genome mRNA array analysis. A common gene signature between WT and S1PR1ΔMΦ TAMs of the two tumor models is shown. P-values were calculated by two-sample t test after applying a variance filter to reduce microarray data complexity. The false discovery rate according to Benjamini and Hochberg was used to account for the multiple testing. Fold changes between the two groups of each supervised analysis were calculated for each gene.