Table 1. Derived variables for in vivo... | Rockefeller University Press

Table 1.

Derived variables for in vivo human monocyte kinetics

Subject	Proliferation	Delay	Lifespans				Pool sizes			Percentage transiting
Subject	BM	BM to blood	marrow	CM	IM	NCM	CM	IM	NCM	CM→IM	IM→NCM
	per d	d	d	d	d	d	%	%	%	%	%
Subject 1	0.48	1.53	1.04	1.37	4.29	6.44	80	8	12	3.2	100
Subject 2	0.28	1.70	1.77	0.5	5.26	7.52	83	7	10	0.8	100
Subject 3	0.26	1.61	1.9	0.62	3.55	8.28	90	3	7	0.6	100
Subject 4	0.64	1.70	0.78	1.54	4.11	N/R	96	2	2	0.8	N/R
Mean	0.42	1.64	1.37	1.01	4.30	7.41	87	5	8	1.4	100
SEM	0.09	0.04	0.27	0.26	0.36	0.53	3.59	1.47	2.17	0.62	0

Subject	Proliferation	Delay	Lifespans				Pool sizes			Percentage transiting
Subject	BM	BM to blood	marrow	CM	IM	NCM	CM	IM	NCM	CM→IM	IM→NCM
	per d	d	d	d	d	d	%	%	%	%	%
Subject 1	0.48	1.53	1.04	1.37	4.29	6.44	80	8	12	3.2	100
Subject 2	0.28	1.70	1.77	0.5	5.26	7.52	83	7	10	0.8	100
Subject 3	0.26	1.61	1.9	0.62	3.55	8.28	90	3	7	0.6	100
Subject 4	0.64	1.70	0.78	1.54	4.11	N/R	96	2	2	0.8	N/R
Mean	0.42	1.64	1.37	1.01	4.30	7.41	87	5	8	1.4	100
SEM	0.09	0.04	0.27	0.26	0.36	0.53	3.59	1.47	2.17	0.62	0

Proliferation rate, lifespans, delays, and percentage of monocyte transitioning between subpopulations by subject for the model in which Δ₃ = 0. Pool sizes were determined by flow cytometric analysis and were an input variable in the model. CMs, classical monocytes; IMs, intermediate monocytes; NCMs, nonclassical monocytes; N/R, data fit not resolved due to low labeling rates in nonclassical monocytes in subject 4.

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