Table 1.
Lymphocyte subsets of P1 (p.N404Y)
1.9 yr of age5 yr of age6.1 yr of age
PatientReference rangePatientReference rangePatientReference range
Absolute lymphocyte count (G/liter) 7.4 2.7–11.9 4.5 1.7–6.9 3.9 1.1–5.9 
CD3+ T cells (cells/μl) 4,600 1,400–8,000 2,831 900–4,500 2,876 700–4,200 
 CD3+HLA-DR+ (%)   3–13 16 3–14 
CD4+ T cells (cells/μl) 3,030 900–5,500 1,716 500–2,400 1,244 300–2,000 
 CD45RA+CCR7+ (%)     78.5 57.4–84.9 
 CD45RACCR7+ (%)     9.8 11.3–26.7 
 CD45RACCR7 (%)     9.1 3.3–15.2 
 CD45RA+CCR7 (%)     1.7 0.4–2.6 
CD8+ T cells (cells/μl) 1,570 400–2,300 1,009 300–1,600 1,459 300–1,800 
 CD45RA+CCR7+ (%)     44.9 28.4–80.6 
 CD45RACCR7+ (%)     1–4.5 
 CD45RACCR7 (%)     6.7 6.2–29.3 
 CD45RA+CCR7 (%)     43.1 9.1–49.1 
CD4/CD8 1.9 1–3 1.7 1–2.1 0.85 0.9–2.6 
CD56+CD16+ NK cells (cells/μl) 110 61–510 99 70–590 231 70–590 
CD19+ B cells (cells/μl) 1,560 529–1,930 1,532 323–1,000 788 212–796 
 CD27IgD+ naive (%)   96 70–86 93 63–89 
 CD27+IgD+ nonswitched memory (%)   3 7–15 3–19 
 CD27+IgD class-switched memory (%)   1 4–16 3 4–17 
1.9 yr of age5 yr of age6.1 yr of age
PatientReference rangePatientReference rangePatientReference range
Absolute lymphocyte count (G/liter) 7.4 2.7–11.9 4.5 1.7–6.9 3.9 1.1–5.9 
CD3+ T cells (cells/μl) 4,600 1,400–8,000 2,831 900–4,500 2,876 700–4,200 
 CD3+HLA-DR+ (%)   3–13 16 3–14 
CD4+ T cells (cells/μl) 3,030 900–5,500 1,716 500–2,400 1,244 300–2,000 
 CD45RA+CCR7+ (%)     78.5 57.4–84.9 
 CD45RACCR7+ (%)     9.8 11.3–26.7 
 CD45RACCR7 (%)     9.1 3.3–15.2 
 CD45RA+CCR7 (%)     1.7 0.4–2.6 
CD8+ T cells (cells/μl) 1,570 400–2,300 1,009 300–1,600 1,459 300–1,800 
 CD45RA+CCR7+ (%)     44.9 28.4–80.6 
 CD45RACCR7+ (%)     1–4.5 
 CD45RACCR7 (%)     6.7 6.2–29.3 
 CD45RA+CCR7 (%)     43.1 9.1–49.1 
CD4/CD8 1.9 1–3 1.7 1–2.1 0.85 0.9–2.6 
CD56+CD16+ NK cells (cells/μl) 110 61–510 99 70–590 231 70–590 
CD19+ B cells (cells/μl) 1,560 529–1,930 1,532 323–1,000 788 212–796 
 CD27IgD+ naive (%)   96 70–86 93 63–89 
 CD27+IgD+ nonswitched memory (%)   3 7–15 3–19 
 CD27+IgD class-switched memory (%)   1 4–16 3 4–17 

Abnormal results are shown in bold.

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