| Patient no. . | Sample no. . | Gender/age . | Clinical diagnosis . | Lesion type . |
|---|---|---|---|---|
| 1 | HSB-2407 | F/58 | Normal | Control |
| 2 | HSB-2803 | M/92 | Dementiaa | Control |
| 3 | HSB-3119 | F/77 | MS diagnosed but not supported by neuropathological diagnosis | Control |
| 4 | HSB-3391 | F/48 | MS; periventricular white matter shows variable demyelination, associated with prominent gliosis and perivascular lymphocytic and macrophage infiltration | Chronic Active MS |
| 5 | HSB-3442 | F/63 | Irregular bilateral periventricular demyelination | Chronic MS |
| 6 | HSB-3704 | F/47 | Extensive white matter demyelination and axonal loss, perivascular lymphocytic cuffing, and extensive gliosis associated with areas of neuronal loss | Chronic Active MS |
| Patient no. . | Sample no. . | Gender/age . | Clinical diagnosis . | Lesion type . |
|---|---|---|---|---|
| 1 | HSB-2407 | F/58 | Normal | Control |
| 2 | HSB-2803 | M/92 | Dementiaa | Control |
| 3 | HSB-3119 | F/77 | MS diagnosed but not supported by neuropathological diagnosis | Control |
| 4 | HSB-3391 | F/48 | MS; periventricular white matter shows variable demyelination, associated with prominent gliosis and perivascular lymphocytic and macrophage infiltration | Chronic Active MS |
| 5 | HSB-3442 | F/63 | Irregular bilateral periventricular demyelination | Chronic MS |
| 6 | HSB-3704 | F/47 | Extensive white matter demyelination and axonal loss, perivascular lymphocytic cuffing, and extensive gliosis associated with areas of neuronal loss | Chronic Active MS |
The clinical pathology of MS and control brain tissues obtained from the UCLA HBSFRC is described. Each brain was evaluated by neuropathologists at UCLA. Brain tissue from three MS cases was examined along with three control brains from cases without MS. In all cases, the tissue was taken from the region around or at the corpus callosum, as shown in Fig. S2.
Dementia with no distinctive pathology.